2-Phosphonooxy-benzoesaeure-amid | 98276-54-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2-Phosphonooxy-benzoesaeure-amid
• 英文别名: phosphoric acid mono-(2-carbamoyl-phenyl ester)；Phosphorsaeure-mono-(2-carbamoyl-phenylester)；2-Phosphonoxy-benzoesaeure-amid；(2-Carbamoylphenyl) dihydrogen phosphate
• CAS: 98276-54-1
• 化学式: C₇H₈NO₅P
• 分子量: 217.118
• InChiKey: IHFMWXPIPHDGTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  110
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  水杨酰胺 在 PPA 作用下， 生成 2-Phosphonooxy-benzoesaeure-amid
  参考文献：
  名称：

  进行酯的形成和转化。八。酸化氨基醇基磷酸酯

  摘要：

  一些氨基烷基磷酸已经通过相应的氨基醇的磷酸化来制备。这些酸已被乙酰化，苯甲酰化和甲苯磺酸化。

  DOI：

  10.1002/hlca.19560390535

文献信息

• Anionic or cationic dendrimer antimicrobial or antiparasitic compositions
  申请人：STARPHARMA LIMITED

  公开号：US20030129158A1

  公开（公告）日：2003-07-10

  To inhibit, prophylactically or therapeutically, a bacterial, yeast, fungal, or parasitic agent in a patient, an effective amount of a dendrimer is administered to the patient, which dendrimer has a plurality of terminal groups, at least one of which has an anionic- or cationic-moiety covalently bonded or linked thereto. The anionic-containing moiety is not a disaccharide or oligosaccharide moiety, and, where the anionic-containing moiety is a neuraminic- or sialic acid-containing moiety, it is modified in the 4-position by substitution with an amino, amido, cyano, azido or guanido group, or is unsaturated.

  为了抑制、预防或治疗患者体内的细菌、酵母菌、真菌或寄生虫，需要向患者注射有效量的树状分子，该树状分子具有多个末端基团，其中至少一个基团与其共价键合或连接成阳离子或阴离子基团。阴离子含有的基团不是二糖或寡糖基团，当阴离子含有的基团是神经酰胺酸或唾液酸含有的基团时，在4位被氨基、酰胺、氰基、叠氮基或鸟氨酸基团取代或不饱和。
• US7572459B2
  申请人：——

  公开号：US7572459B2

  公开（公告）日：2009-08-11
• [EN] CAPROLACTAM DERIVATIVES AND USES THEREOF<br/>[FR] DERIVES DE CAPROLACTAM ET LEURS UTILISATIONS
  申请人：ARIAD PHARMA INC

  公开号：WO2001068655A2

  公开（公告）日：2001-09-20

  The invention involves derivatives of caprolactam of the formula (I) in which [A?1], A2 and R1¿ have the meanings indicated in the description, their salts and their prodrugs. The invention also relates to the preparation of such compounds, synthetic intermediates, their use, and in particular, antagonists of the Src SH2 domain and inhibitors of bone resorption and pharmaceutical compounds containing such compounds.
• Recherches sur la formation et la transformation des esters. VIII. Préparation d'acides aminoalcoyl-phosphoriques et de leurs dérivés N-acylés
  作者：Emile Cherbuliez、J. Rabinowitz

  DOI：10.1002/hlca.19560390535

  日期：——

  Some aminoalkylphosphoric acids have been prepared by phosphorylation of the corresponding amino alcohols. These acids have been acetylated, benzoylated and tosylated.

  一些氨基烷基磷酸已经通过相应的氨基醇的磷酸化来制备。这些酸已被乙酰化，苯甲酰化和甲苯磺酸化。