2-[2-(Dimethylamino)ethoxy]-1,3,2lambda~5~-dioxaphospholan-2-one | 101707-61-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2-[2-(Dimethylamino)ethoxy]-1,3,2lambda~5~-dioxaphospholan-2-one
• 英文别名: N,N-dimethyl-2-[(2-oxo-1,3,2λ5-dioxaphospholan-2-yl)oxy]ethanamine
• CAS: 101707-61-3
• 化学式: C₆H₁₄NO₄P
• 分子量: 195.15
• InChiKey: YJKIBRDMKHRECH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  48
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• MEDICAL COPOLYMERS
  申请人：Ippoliti J. Thomas

  公开号：US20090324679A1

  公开（公告）日：2009-12-31

  According to an aspect of the present invention, medical copolymers are provided which comprise (a) a polymer backbone comprising (i) a plurality of —C═C— groups within the polymer backbone, (ii) a plurality of -R 9 - groups within the polymer backbone, wherein R 9 comprises a radical-substituted C2-C10 cyclic or heterocyclic group, or (iii) both a plurality of —C═C— groups and a plurality of -R 9 - groups within the polymer backbone (b) a plurality of hydrocarbon-based pendant groups along the polymer backbone that comprise a saturated or unsaturated carbon chain of at least four carbons in length, and (c) a plurality of zwitterionic pendant groups along the polymer backbone that comprise a positively charged quaternary ammonium group and a negatively charged phosphate group. Further aspects of the invention, among others, relate to methods of forming such copolymers, medical products that contain such copolymers, and methods of making such medical products.
• US8187623B2
  申请人：——

  公开号：US8187623B2

  公开（公告）日：2012-05-29