硼酸钠盐

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 碱金属含氧阴离子化合物
• 中文名称: 硼酸钠盐
• 英文名称: trisodium;borate
• 化学式: BNa3O3
• 分子量: 127.78
• InChiKey: BSVBQGMMJUBVOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -12.94
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  69.2
• 氢给体数：
  0
• 氢受体数：
  3

ADMET

毒理性

• 副作用

神经毒素 - 其他中枢神经系统神经毒素 职业性肝毒素 - 继发性肝毒素：在职业环境中潜在毒性效应基于人类摄入或动物实验的中毒案例。 生殖毒素 - 对生殖系统有毒的化学物质，包括后代缺陷以及损伤男性或女性生殖功能。生殖毒性包括发育效应。参见生殖毒性风险评估指南。

Neurotoxin - Other CNS neurotoxin Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male or female reproductive function. Reproductive toxicity includes developmental effects. See Guidelines for Reproductive Toxicity Risk Assessment.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

反应信息

• 作为反应物：
  描述：

  硼酸钠盐 、 氢氧化钙 生成 tricalcium;boron(3+);triperoxide
  参考文献：
  名称：

  IZUMIDA TATSUO; KAWAMURA FUMIO; CHINO KOICHI; KIKUCHI MAKOTO, NUCL. TECHNOL., 78,(1987) N 2, 185-190

  摘要：

  DOI：
• 作为试剂：
  描述：

  4-硝基苯甲醛肟 、 、 氢气 、 、 sodium hydroxide 在 铂 氢气 、 甲醇 、 硼酸钠盐 作用下， 以 甲醇 为溶剂， 反应 13.5h， 生成 4-氨基苄胺
  参考文献：
  名称：

  Process for producing aminobenzylamines

  摘要：

  Aminobenzylamines是通过在有机溶剂中存在以下化合物的情况下催化还原o-，m-或p-硝基苯甲醛肟而产生的：(a)硼酸，磷酸和/或其酐，(b)二氧化碳气体和(c)有机酸。起始物质硝基苯甲醛肟是通过将相应的硝基苯甲醛与羟胺反应而产生的。

  公开号：

  US04751328A1

文献信息

• Boron-containing wood preservatives
  申请人：Kerr-McGee Chemical Corporation

  公开号：US04719110A1

  公开（公告）日：1988-01-12

  The present invention provides for boron-containing wood preserving solutions and a method for their preparation. The wood preserving solutions of the invention are noncrystallizable at ambient temperatures and are prepared from a dispersion of a particulated sodium tetraborate, phosphoric acid and water by heating the dispersion at elevated temperatures and for a period of time sufficient to provide a clear solution. The particulated sodium tetraborate and phosphoric are present in the dispersion in a specific molar ratio of 5:3, said ratio being critical to achieving the noncrystallizable characteristic of the wood preserving solutions of the invention.

  本发明提供了含硼木材防腐溶液及其制备方法。本发明的木材防腐溶液在常温下不结晶，并由颗粒状的四硼酸钠、磷酸和水的分散液通过在高温下加热一段时间而制备而成。所述颗粒状的四硼酸钠和磷酸以一定的摩尔比（5:3）存在于分散液中，该比例对于实现本发明的木材防腐溶液的不结晶特性是至关重要的。
• Process for preparing phosphorothioates and phenylphosphonothioates
  申请人：The Dow Chemical Company

  公开号：US04016225A1

  公开（公告）日：1977-04-05

  Mixtures of (1) a quaternary ammonium salt(s) and (2) 1,4-diazabicyclo[2.2.2]octane are novel catalysts in the process of reacting an alkali metal phenate, pyridinate or pyrimidiate with an O,O-dialkyl phosphorochloridothioate or O-alkyl phenylphosphonochloridothioate to produce the corresponding phosphorothioates and phenylphosphonothioates. The process is conducted under alkaline conditions in a liquid reaction medium. As an example, O,O-diethyl 0-(3,5,6-trichloro-2-pyridyl)phosphorothioate is prepared in excellent yields and purity by reacting sodium 3,5,6-trichloropyridinate with O,O-diethyl phosphorochloridothioate in a stirred methylene chloride-water reaction medium in the presence of a catalytic amount of benzyltriethylammonium chloride and 1,4-diazabicyclo[2.2.2]octane.

  混合物（1）季铵盐和（2）1,4-二氮杂双环[2.2.2]辛烷是在碱性条件下，在液态反应介质中反应碱金属苯酚盐，吡啶盐或嘧啶盐与O,O-二烷基磷酰氯硫代酸酯或O-烷基苯基膦酸氯硫代酸酯以产生相应的磷酸硫代酯和苯基膦酸硫代酯的新型催化剂。例如，通过在搅拌的氯甲烷-水反应介质中，在苄基三乙基铵氯和1,4-二氮杂双环[2.2.2]辛烷的催化下，将三氯吡啶钠与O,O-二乙基磷酰氯硫代酸酯反应，可以制备出优良的产率和纯度的O,O-二乙基0-(3,5,6-三氯-2-吡啶基)磷酸硫代酯。
• Preparation for endermism containing dopamine derivatives
  申请人：Sansho Co., Ltd.

  公开号：US05246949A1

  公开（公告）日：1993-09-21

  (A) a diacylated dopamine derivative represented by the formula (I): ##STR1## wherein R.sup.1 represents an alkyl group having 3 to 7 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, substituted or unsubstituted phenyl group or a substituted or unsubstituted nitrogen-containing heterocyclic group; and R.sup.2 represents a hydrogen atom or a lower alkyl group; or a salt thereof; and (B) one or more compounds selected from lactic acid esters, fatty acid monoglycerides and higher alcohols; optionally together with (C) an unsaturated fatty acid monohydric alcohol ester. This preparation has a sustained effect, a high skin permeability and a low skin irritativeness.

  （A）一种由公式（I）表示的二酰基多巴胺衍生物：##STR1## 其中，R1代表具有3至7个碳原子的烷基基团，具有3至6个碳原子的环烷基基团，取代或未取代的苯基团或取代或未取代的含氮杂环基团；R2代表氢原子或较低的烷基基团；或其盐；以及（B）选自乳酸酯，脂肪酸单甘酯和较高醇的一种或多种化合物；可选地与（C）不饱和脂肪酸单羟基醇酯一起。该制剂具有持久的效果，高皮肤渗透性和低皮肤刺激性。
• Anaphylatoxin receptor ligands containing lipophilic residues
  申请人：Abbott Laboratories

  公开号：US05663148A1

  公开（公告）日：1997-09-02

  Oligopeptide compounds or oligopeptide analague compounds of the formula, A-B-D-E-G-J-L-M-N(R.sup.4)Arg-OH, which are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states, as well as anaphylatoxin receptor ligand compositions and a method for modulating anaphylatoxin activity.

  寡肽化合物或寡肽类似物的化学式为A-B-D-E-G-J-L-M-N(R.sup.4)Arg-OH，它们是过敏毒素受体的配体，可用于治疗炎症性疾病状态，以及过敏毒素受体配体组合物和调节过敏毒素活性的方法。
• Process for preparation of sodium percarbonate or sodium perborate of
  申请人：Kao Soap Co., Ltd.

  公开号：US04071462A1

  公开（公告）日：1978-01-31

  Sodium percarbonate or sodium perborate of high specific volume is prepared by mixing sodium carbonate or sodium borate, or an aqueous solution thereof, with aqueous hydrogen peroxide, in the presence of an anionic surface active agent in an amount exceeding the critical concentration for micelle formation.

  高比体积的过碳酸钠或过硼酸钠是通过将碳酸钠或硼酸钠或其水溶液与过氧化氢混合，在阴离子表面活性剂存在下，其用量超过胶束形成的临界浓度来制备的。