2-ethoxy-4-methyl-1,3,2-dioxaphospholane 2-oxide | 697-36-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2-ethoxy-4-methyl-1,3,2-dioxaphospholane 2-oxide
• 英文别名: 2-ethoxy-4-methyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholane；Phosphorigsaeure-methylester-(3-methoxy-propylenester)；2-Aethoxy-4-methyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan；2-Ethoxy-4-methyl-1,3,2lambda5-dioxaphospholane 2-oxide；2-ethoxy-4-methyl-1,3,2λ5-dioxaphospholane 2-oxide
• CAS: 697-36-9
• 化学式: C₅H₁₁O₄P
• 分子量: 166.114
• InChiKey: QYDKVZKBJZYXHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-ethoxy-4-methyl-1,3,2-dioxaphospholane 2-oxide 以 氘代氯仿 为溶剂， 反应 48.0h， 生成 propylene hydrogen phosphate
  参考文献：
  名称：

  Reaction of epoxides with metaphosphoric acid derivatives

  摘要：

  Ethyl metaphosphate (EtOPO2), eliminated in the thermolysis of the bridged cyclic phosphonate endo-3-ethoxy-6-methyl-N-phenyl-2,3-oxaphosphabicyclo[2.2.2]oct-5-ene-8,9-dicarboximide 3-oxide, has been found to cause ring opening of epoxides, resulting in formation of 2-ethoxy-4-substituted 1,3,2-dioxaphospholane 2-oxides as major products. N,N-Diethyl metaphosphoramidate (Et2NPO2) reacted similarly. With ethyl metathiophosphate (EtOP(S)O), the 1,3,2-oxathiaphospholane 2-oxide ring was formed. Products of these reactions were characterized by P-31 NMR spectroscopy and by GC-MS. These reactions are presumed to be initiated by electrophilic attack of the metaphosphate on the epoxide oxygen to form a cyclic oxonium ion.

  DOI：

  10.1021/jo00008a017
• 作为产物：
  描述：

  2-ethoxy-4-methyl-1,3,2-dioxaphospholane 在 dinitrogen tetraoxide 作用下， 生成 2-ethoxy-4-methyl-1,3,2-dioxaphospholane 2-oxide
  参考文献：
  名称：

  Cyclic phosphate and phosphite triesters - A P31 N.M.R. study

  摘要：

  DOI：

  10.1016/s0040-4039(00)70438-2

文献信息

• Arbusow; Soroastrowa; Rispoloshenski, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1948, p. 208
  作者：Arbusow、Soroastrowa、Rispoloshenski

  DOI：——

  日期：——
• Cyclic phosphate and phosphite triesters - A P31 N.M.R. study
  作者：G.M. Blackburn、J.S. Cohen、Lord Todd

  DOI：10.1016/s0040-4039(00)70438-2

  日期：1964.1
• Quin, Louis D.; Sadanani, Narayan D.; Bourdieu, Catherine, Phosphorus, Sulfur and Silicon and the Related Elements, 1990, vol. 49/50, p. 313 - 316
  作者：Quin, Louis D.、Sadanani, Narayan D.、Bourdieu, Catherine、Wu, Xiao-Ping、Quin, Gyongyi S.、Bodalski, Ryszard

  DOI：——

  日期：——
• Mizrakh,L.I. et al., Journal of general chemistry of the USSR, 1972, vol. 42, p. 1690 - 1694
  作者：Mizrakh,L.I. et al.

  DOI：——

  日期：——
• RIESEL, L.;LINDEMANN, D., Z. ANORG. UND ALLG. CHEM., 591,(1990) N2, C. 214-220
  作者：RIESEL, L.、LINDEMANN, D.

  DOI：——

  日期：——