3,3-diethoxy-2-hydroxypropyl dihydrogen phosphate | 29902-73-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 3,3-diethoxy-2-hydroxypropyl dihydrogen phosphate
• 英文别名: (3,3-Diethoxy-2-hydroxypropyl) dihydrogen phosphate
• CAS: 29902-73-6
• 化学式: C₇H₁₇O₇P
• 分子量: 244.182
• InChiKey: WUTWKLGSMFCXAH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  环氧丙烯醛缩二乙醇 在 dipotassium hydrogenphosphate 、 水 作用下， 生成 3,3-diethoxy-2-hydroxypropyl dihydrogen phosphate
  参考文献：
  名称：

  Ukita; Nagasawa, Chemical and pharmaceutical bulletin, 1959, vol. 7, p. 383

  摘要：

  DOI：

文献信息

• METABOLICALLY ENGINEERED MICRO-ORGANISMS HAVING REDUCED PRODUCTION OF UNDESIRED METABOLIC PRODUCTS
  申请人：Fluxome Sciences AS

  公开号：EP1565554A1

  公开（公告）日：2005-08-24
• Metabolically engineered micro-organisms having reduced production of undesired metabolic products
  申请人：Bro Christoffer

  公开号：US20060257983A1

  公开（公告）日：2006-11-16

  A metabolically engineered micro-organism has an operative first metabolic pathway in which a first metabolite is transformed into a second metabolite in a reaction in which NAD is a cofactor for a first enzyme, suitably a phosphorylating dehydrogenase, said reaction step producing NADH. Said second metabolite is transformed into at least one further metabolite in a reaction catalysed by a second enzyme, suitably a kinase. The organism has an operative second metabolic pathway characterised by an enzyme activity in excess of a native level in respect of a third enzyme, suitably a non-phosphorylating dehydrogenase, e.g. GAPN, catalysing a non-reversible reaction in which NADP is a cofactor and NADPH is a product. Said first metabolite is transformed into a said further metabolite without the involvement of said second enzyme.
• US4171244A
  申请人：——

  公开号：US4171244A

  公开（公告）日：1979-10-16
• [EN] METABOLICALLY ENGINEERED MICRO-ORGANISMS HAVING REDUCED PRODUCTION OF UNDESIRED METABOLIC PRODUCTS<br/>[FR] MICRO-ORGANISMES PRODUITS PAR INGENIERIE METABOLIQUE AYANT UNE PRODUCTION REDUITE DE PRODUITS METABOLIQUES INDESIRABLES
  申请人：FLUXOME SCIENCES AS

  公开号：WO2004048559A1

  公开（公告）日：2004-06-10

  A metabolically engineered micro-organism has an operative first metabolic pathway in which a first metabolite is transformed into a second metabolite in a reaction in which NAD is a cofactor for a first enzyme, suitably a phosphorylating dehydrogenase, said reaction step producing NADH. Said second metabolite is transformed into at least one further metabolite in a reaction catalysed by a second enzyme, suitably a kinase. The organism has an operative second metabolic pathway characterised by an enzyme activity in excess of a native level in respect of a third enzyme, suitably a non-phosphorylating dehydrogenase, e.g. GAPN, catalysing a non-reversible reaction in which NADP is a cofactor and NADPH is a product. Said first metabolite is transformed into a said further metabolite without the involvement of said second enzyme.
• Ukita; Nagasawa, Chemical and pharmaceutical bulletin, 1959, vol. 7, p. 383
  作者：Ukita、Nagasawa

  DOI：——

  日期：——