Di-tert-butyl vic-disulfoxide | 79599-55-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 亚磺酰基化合物
• 英文名称: Di-tert-butyl vic-disulfoxide
• 英文别名: InChI=1/C8H18O2S2/c1-7(2,3)11(9)12(10)8(4,5)6/h1-6H；2-tert-butylsulfinylsulfinyl-2-methylpropane
• CAS: 79599-55-6
• 化学式: C₈H₁₈O₂S₂
• 分子量: 210.362
• InChiKey: SVALMIZTILEPBL-UHFFFAOYSA-N

物化性质

• 沸点：
  325.4±25.0 °C(Predicted)
• 密度：
  1.170±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  72.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  (S)-(-)-叔丁烷硫代亚磺酸叔丁酯 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 生成 2-methyl-2-propanesulfenic acid 、 Di-tert-butylsulfinic anhydride 、 Di-tert-butyl vic-disulfoxide
  参考文献：
  名称：

  Detection and Decomposition of Di-tert-butyl Disulfide-Polyoxide Derivatives

  摘要：

  The chemistry of di-tert-butyl disulfide polyoxide derivatives has been investigated. Low-temperature experiments permit the clear detection of vic-disulfoxides (alpha-disulfoxides). In addition, a proposal for a decomposition mechanism that accounts for the detection of one of the diastereoisomers and the formation of the final products has been advanced. The formation of di-tert-butyl thiosulfonate was also shown to be solvent and concentration dependent. Finally, low-temperature experiments permit the detection of the sulfinyl sulfone and vic-disulfone derivatives. A general mechanism has been proposed for the decomposition of these disulfide polyxoide derivatives.

  DOI：

  10.1021/jo00109a042

文献信息

• TRICYCLIC QUINOLINE AND QUINOXALINE DERIVATIVES
  申请人：ABBVIE DEUTSCHLAND GMBH & CO. KG

  公开号：US20140080813A1

  公开（公告）日：2014-03-20

  The present invention relates to tricyclic quinoline and quinoxaline derivatives, to a pharmaceutical composition containing such compounds, to their use as modulators, especially agonists or partial agonists, of the 5-HT 2C receptor, their use for preparing a medicament for the prevention or treatment of conditions and disorders which respond to the modulation of 5-HT 2C receptor, and to a method for preventing or treating conditions and disorders which respond to the modulation of 5-HT 2C receptor.

  本发明涉及三环喹啉和喹啉衍生物，涉及含有这些化合物的药物组合物，以及它们作为5-HT2C受体调节剂，特别是激动剂或部分激动剂的用途，用于制备用于预防或治疗对5-HT2C受体调节有反应的病症和紊乱的药物，以及用于预防或治疗对5-HT2C受体调节有反应的病症和紊乱的方法。
• Isoxazoline compounds for combating invertebrate pests
  申请人：Koerber Karsten

  公开号：US20120030841A1

  公开（公告）日：2012-02-02

  The present invention relates to isoxazoline compounds which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

  本发明涉及一种异氧杂环化合物，其可用于对抗或控制无脊椎动物害虫，特别是节肢动物害虫和线虫。本发明还涉及一种使用这些化合物控制无脊椎动物害虫的方法，以及包括该化合物的植物繁殖材料、农业和兽医组合物。
• Azoline Compounds for Combating Invertebrate Pests
  申请人：Koerber Karsten

  公开号：US20120291159A1

  公开（公告）日：2012-11-15

  The present invention relates to azoline compounds which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

  本发明涉及一种氮杂环化合物，其对无脊椎动物害虫，特别是节肢动物害虫和线虫的控制和防治具有用途。本发明还涉及一种使用这些化合物控制无脊椎动物害虫的方法，以及包括该化合物的植物繁殖材料和农业和兽医组合物。
• N-Thio-Anthranilamide Compounds and Their Use as Pesticides
  申请人：Kaiser Florian

  公开号：US20140155264A1

  公开（公告）日：2014-06-05

  The present invention relates to N-thio-anthranilamide compounds of the formula (I), the stereoisomers, the salts, the tautomers and the N-oxides thereof, wherein R 1 is halogen or halomethyl; R 2 is hydrogen, halogen or cyano; R 3 is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, C 2 -C 6 -alkenyl or the like; R 4 is halogen; R 5 and R 6 independently of each other are optionally substituted C 1 -C 6 -alkyl, C 3 -C 6 -cycloalkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, phenyl, or together represent an (hetero)aliphatic chain, or the like; k is 0 or 1. The present invention further relates to a method for combating or controlling invertebrate pests, to a method for protecting plant propagation material and/or the plants which grow therefrom, to plant propagation material comprising at least one compound according to the present invention, to a method for treating or protecting an animal from infestation or infection by parasites, to a process for the preparation of a composition for treating infested or infected animals and/or for protecting animals against infestation or infection by parasites, and to a compound according to the invention for use as a medicament.

  本发明涉及公式（I）的N-硫基蒽酰胺化合物，其立体异构体，盐，互变异构体和N-氧化物，其中R1是卤素或卤甲基; R2是氢，卤素或氰基; R3是氢，C1-C4烷基，C1-C4卤代烷基，C2-C6烯基或类似物; R4是卤素; R5和R6独立地是可选的取代C1-C6烷基，C3-C6环烷基，C2-C6烯基，C2-C6炔基，苯基或共同表示（杂）脂肪链或类似物; k为0或1。本发明还涉及一种用于对抗或控制无脊椎动物害虫的方法，一种用于保护植物繁殖材料和/或从中生长的植物的方法，包括至少一种根据本发明的化合物的植物繁殖材料，一种用于治疗或保护动物免受寄生虫感染的方法，一种用于制备用于治疗受感染或感染动物和/或保护动物免受寄生虫感染的组合物的方法，以及用于作为药物的本发明化合物。
• Aniline Type Compounds
  申请人：Koerber Karsten

  公开号：US20140155451A1

  公开（公告）日：2014-06-05

  The present invention relates to compounds of the formula (I) wherein R 1 and R 2 independently of one another are hydrogen, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 10 -cycloalkyl, C 3 -C 10 -halocycloalkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl or together represent an aliphatic chain, or the like; R 3 is halogen, cyano, C 1 -C 8 -alkyl, C 1 -C 8 -haloalkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -halocycloalkyl, C 2 -C 8 -alkenyl, C 2 -C 8 -haloalkenyl, C 1 -C 8 -alkoxy, phenyl, or the like; R 4 is hydrogen, C 1 -C 10 -alkyl, C 1 -C 10 -haloalkyl, C 3 -C 8 -cycloalkyl, C 3 -C 8 -halocycloalkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl, phenyl, or the like; t is 0 or 1; p is 0, 1, 2, 3 or 4. The present invention also relates to a process for preparing a compound of the formula (I) which comprises reacting a compound of the formula II with a compound of the formulae III or IV: where t, p, R 1 R 3 , R 3 and R 4 are as defined in any of claims 1 to 6 and where A − is an equivalent of an anion having a pK B of at least 10 (determined under standard conditions in water).

  本发明涉及式(I)的化合物，其中R1和R2独立地是氢，C1-C10-烷基，C1-C10-卤代烷基，C3-C10-环烷基，C3-C10-卤代环烷基，C2-C10-烯基，C2-C10-卤代烯基或一起代表脂肪链等；R3是卤素，氰基，C1-C8-烷基，C1-C8-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C8-烯基，C2-C8-卤代烯基，C1-C8-烷氧基，苯基或类似物；R4是氢，C1-C10-烷基，C1-C10-卤代烷基，C3-C8-环烷基，C3-C8-卤代环烷基，C2-C10-烯基，C2-C10-卤代烯基，苯基或类似物；t为0或1；p为0、1、2、3或4。本发明还涉及一种制备式(I)化合物的方法，该方法包括将式II的化合物与式III或IV的化合物反应：其中t、p、R1、R3、R3和R4如权利要求1至6中的任何一项中所定义，A-是至少具有10的pKB（在水中标准条件下测定）的阴离子当量。

表征谱图