2-Propenoic acid, 2-methyl-, phosphinicobis[oxy(1-methyl-2,1-ethanediyl)] ester | 175159-67-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2-Propenoic acid, 2-methyl-, phosphinicobis[oxy(1-methyl-2,1-ethanediyl)] ester
• 英文别名: 1-[hydroxy-[2-(2-methylprop-2-enoyloxy)propoxy]phosphoryl]oxypropan-2-yl 2-methylprop-2-enoate
• CAS: 175159-67-8
• 化学式: C₁₄H₂₃O₈P
• 分子量: 350.3
• InChiKey: LBMQDIISWWRMME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  23
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  108
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• Photo-curable reparative material for dental use
  申请人：——

  公开号：US20030162863A1

  公开（公告）日：2003-08-28

  A photocurable dental restorative comprising (i) 100 parts by weight of a polymerizable monomer, (ii) 0.01 to 5 parts by weight of a photopolymerization initiator of acylphosphine oxide, and (iii) 200 to 1900 parts by weight of an inorganic filler, wherein the inorganic filler (iii) is a mixed filler of: (A) irregular-shaped inorganic particles having an average particle size of not smaller than 0.1 &mgr;m but smaller than 1 &mgr;m; (B) spherical inorganic particles having an average primary particle size of not smaller than 0.1 &mgr;m but not larger than 5 &mgr;m; and (C) fine inorganic particles having an average primary particle size of not larger than 0.1 &mgr;m; which are so blended as to satisfy the following mass ratios circle over (1)} to circle over (3)}: mA /( mB+mC )=0.2 to 3  circle over (1)} mB /( mB+mC )=0.5 to 0.99  circle over (2)} mC /( mB+mC )=0.01 to 0.5  circle over (3)} where mA, mB and mC are masses of the inorganic particles (A) to (C). The restorative features excellent handling property, and makes it possible to obtain a cured product having a high fracture toughness and excellently glossy surface.

  一种光固化牙科修复材料，包括（i）100份重量的可聚合单体，（ii）0.01至5份重量的酰基膦氧化物光聚合引发剂，和（iii）200至1900份重量的无机填料，其中无机填料（iii）是以下混合填料：（A）具有平均粒径不小于0.1μm但小于1μm的不规则形状无机颗粒；（B）具有平均初级粒径不小于0.1μm但不大于5μm的球形无机颗粒；和（C）具有平均初级粒径不大于0.1μm的细微无机颗粒；这些颗粒混合以满足以下质量比圆圈1}至圆圈3}：mA/(mB+mC)=0.2至3；mB/(mB+mC)=0.5至0.99；mC/(mB+mC)=0.01至0.5；其中mA、mB和mC分别为无机颗粒（A）至（C）的质量。该修复材料具有出色的操作性能，可以获得具有高断裂韧性和极佳光泽表面的固化产品。
• [EN] TRICYCLIC OXAZOLIDINONE ANTIBIOTIC COMPOUNDS<br/>[FR] COMPOSÉS ANTIBIOTIQUES OXAZOLIDINONE TRICYCLIQUE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2010041194A1

  公开（公告）日：2010-04-15

  The invention relates to antibacterial compounds of formula (I) wherein “-----” is a bond or is absent, V is CH, CR 6 or N; R 0 is H or, if “-----” is a bond, may also be alkoxy; R 1 is notably H or halogen; U is CH or N when “-----” is a bond, or, if “-----” is absent, U is CH 2, NH or NR 9; R 2 is H, alkylcarbonyl or –CH 2 -R 3; R 3 is H, alkyl or hydroxyalkyl; R 4 is H or, if n is not 0 and R 5 is H, may also be OH; R 5 is H, alkyl, hydroxyalkyl, aminoalkyl, alkoxyalkyl, carboxy or alkoxycarbonyl; R 6 is hydroxyalkyl, carboxy, alkoxycarbonyl or -(CH 2 ) q -NR 7 R 8, q being 1, 2 or 3 and each of R 7 and R 8 independently being H or alkyl or R 7 and R 8 forming with the N atom bearing them a ring; R 9 is alkyl or hydroxyalkyl; A is -(CH 2 ) p -, -CH 2 CH 2 CH(OH)- or -COCH 2 CH(OH)-; G is substituted phenyl or G 1 or G 2, wherein Q is O or S and X is CH or N; and Y 1, Y 2 and Y 3 may each be CH or N; and n is 0 when A is -CH 2 CH 2 CH(OH)- or -COCH 2 CH(OH)-, and n is 0, 1 or 2 when A is -(CH 2 ) p -, p being 1, 2, 3 or 4, with the proviso that the sum of n and p is then 2, 3 or 4; and to salts of such compounds.

  该发明涉及式(I)的抗菌化合物，其中“-----”是键或不存在，V是CH，CR 6或N; R 0是H或如果“-----”是键，则也可以是烷氧基; R 1主要是H或卤素; 当“-----”是键时，U是CH或N，或者如果“-----”不存在，则U是CH 2，NH或NR 9; R 2是H，烷基羰基或-CH 2 -R 3; R 3是H，烷基或羟基烷基; R 4是H或如果n不为0且R 5为H，则也可以是OH; R 5是H，烷基，羟基烷基，氨基烷基，烷氧基烷基，羧基或烷氧羰基; R 6是羟基烷基，羧基，烷氧羰基或-(CH 2 ) q -NR 7 R 8，其中q为1、2或3，且R 7和R 8中的每一个独立地是H或烷基，或R 7和R 8与携带它们的N原子形成一个环; R 9是烷基或羟基烷基; A是-(CH 2 ) p-，-CH 2 CH 2 CH(OH)-或-COCH 2 CH(OH)-; G是取代苯基或G 1或G 2，其中Q是O或S，X是CH或N; Y 1、Y 2和Y 3每个可以是CH或N; 当A为-CH 2 CH 2 CH(OH)-或-COCH 2 CH(OH)-时，n为0，当A为-(CH 2 ) p-，p为1、2、3或4时，n为0、1或2，但n和p的总和为2、3或4; 以及这些化合物的盐。
• Process for manufacturing information recording media and the information recording media
  申请人：——

  公开号：US20010046644A1

  公开（公告）日：2001-11-29

  The invention relates to a process for manufacturing information recording media by adhering two disks, at least one of which possesses an information recording layer, wherein a radically polymerizable photocurable resin composition is put between the two disks and the resin composition is cured to adhere the disks by irradiating light from the external periphery edge and/or internal periphery edge of said disks, wherein the resin composition has a light absorbance of 12 or less at a wavelength of 360-45 nm.

  本发明涉及一种通过粘接两个盘片制造信息记录介质的工艺，其中至少一个盘片具有信息记录层，将一种基于自由基聚合的光固化树脂组合物放置在两个盘片之间，并通过从所述盘片的外周边缘和/或内周边缘照射光线来固化树脂组合物以粘接盘片，其中所述树脂组合物在360-450nm波长处的光吸收度为12或以下。
• DENTAL CURABLE COMPOSITION
  申请人：TOKUYAMA CORPORATION

  公开号：EP1226807A1

  公开（公告）日：2002-07-31

  A dental polymerizable and curable composition that can be used as a dental composite restorative featuring excellent handling property at the time of filling, a small contraction upon polymerization, a high bending strength, excellent surface smoothness and wear resistance, and a very good matching of color tone to the natural tooth after restored.

  一种牙科可聚合固化组合物，可用作牙科复合材料修复体，在填充时具有极佳的操作性能，聚合时收缩小，弯曲强度高，表面光滑度和耐磨性极佳，修复后与天然牙的色调非常匹配。
• PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE
  申请人：TOKUYAMA CORPORATION

  公开号：EP1236459A1

  公开（公告）日：2002-09-04

  A photocurable dental restorative comprising (i) 100 parts by weight of a polymerizable monomer, (ii) 0.01 to 5 parts by weight of a photopolymerization initiator of acylphosphine oxide, and (iii) 200 to 1900 parts by weight of an inorganic filler, wherein the inorganic filler (iii) is a mixed filler of: (A) irregular-shaped inorganic particles having an average particle size of not smaller than 0.1 µm but smaller than 1 µm; (B) spherical inorganic particles having an average primary particle size of not smaller than 0.1 µm but not larger than 5 µm; and (C) fine inorganic particles having an average primary particle size of not larger than 0.1 µm;    which are so blended as to satisfy the following mass ratios ① to ③: ① mA/ (mB + mC) = 0.2 to 3 ② mB/(mB + mC) = 0.5 to 0.99 ③ mC/(mB + mC) = 0.01 to 0.5    where mA, mB and mC are masses of the inorganic particles (A) to (C). The restorative features excellent handling property, and makes it possible to obtain a cured product having a high fracture toughness and excellently glossy surface.

  一种光固化牙科修复体，包括(i)100 份（按重量计）可聚合单体，(ii)0.01 至 5 份（按重量计）酰基氧化膦光聚合引发剂，以及(iii)200 至 1900 份（按重量计）无机填料，其中无机填料(iii)是以下物质的混合填料： (A) 平均粒径不小于 0.1 微米但小于 1 微米的不规则无机颗粒； (B) 平均主粒径不小于 0.1 微米但不大于 5 微米的球形无机颗粒；以及 (C) 平均主要粒径不大于 0.1 微米的细无机颗粒； 混合后满足以下质量比①至③： ① mA/ (mB + mC) = 0.2 至 3 ② mB/(mB + mC) = 0.5 至 0.99 ③ mC/(mB + mC) = 0.01 至 0.5 其中 mA、mB 和 mC 为无机颗粒（A）至（C）的质量。 该修复剂具有极佳的操作性能，可获得具有高断裂韧性和极佳表面光泽的固化产品。