methyl 2-propyl phosphate | 62406-63-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: methyl 2-propyl phosphate
• 英文别名: phosphoric acid isopropyl ester methyl ester；Phosphorsaeure-isopropylester-methylester；Isopropyl methylphosphoric acid；methyl propan-2-yl hydrogen phosphate
• CAS: 62406-63-7
• 化学式: C₄H₁₁O₄P
• 分子量: 154.103
• InChiKey: SHAKYODQWMUEPY-UHFFFAOYSA-N

物化性质

• 沸点：
  192.6±23.0 °C(Predicted)
• 密度：
  1.191±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  Methyl-isopropyl-p-nitrophenyl-phosphorsaeureester 在 organophosphorus acid anhydrolase from Alteromonas sp. JD_6.5 、 水 作用下， 生成 对硝基苯酚 、 methyl 2-propyl phosphate
  参考文献：
  名称：

  Substrate and stereochemical specificity of the organophosphorus acid anhydrolase from Alteromonas sp. JD6.5 toward p -nitrophenyl phosphotriesters

  摘要：

  The enzyme OPAA hydrolyzes p-nitrophenyl phosphotriesters bearing substituents at the phosphorus center ranging in size from methyl to phenyl. The enzyme exhibits stereoselectivity toward the hydrolysis of chiral substrates with a preference for the Sp enantiomer. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(00)00213-4

文献信息

• Phosphorylation of alcohols through the acid-catalysed fragmentation of α-oxyiminophosphonates
  作者：Eli Breuer、Rafik Karaman、Haim Leader、Amiram Goldblum

  DOI：10.1039/c39870000671

  日期：——

  The acid-catalysed fragmentation of monoalkyl α-oxyiminophosphonates results in the formation of (mixed) phosphodiesters and a nitrile in high yields.

  α-氧亚氨基膦酸单烷基酯的酸催化断裂导致高产率地形成（混合的）磷酸二酯和腈。
• Katzhendler, Jehoshua; Schneider, Hava; Ta-Shma, Rachel, Journal of the Chemical Society. Perkin Transactions 2 (2001), 2000, # 9, p. 1961 - 1968
  作者：Katzhendler, Jehoshua、Schneider, Hava、Ta-Shma, Rachel、Breuer, Eli

  DOI：——

  日期：——
• Katzhendler, Jehoshua; Karaman, Rafik; Gibson, Dan, Journal of the Chemical Society. Perkin transactions II, 1989, p. 589 - 594
  作者：Katzhendler, Jehoshua、Karaman, Rafik、Gibson, Dan、Breuer, Eli、Leader, Haim

  DOI：——

  日期：——
• KATZHENDLER, JEHOSHUA;KARAMAN, RAFIK;GIBSON, DAN;BREUER, ELI;LEADER, HAIM, J. CHEM. SOC. PERKIN TRANS. PT 2,(1989) N, C. 529-594
  作者：KATZHENDLER, JEHOSHUA、KARAMAN, RAFIK、GIBSON, DAN、BREUER, ELI、LEADER, HAIM

  DOI：——

  日期：——
• Substrate and stereochemical specificity of the organophosphorus acid anhydrolase from Alteromonas sp. JD6.5 toward p -nitrophenyl phosphotriesters
  作者：Craig M. Hill、Feiyue Wu、Tu-Chen Cheng、Joseph J. DeFrank、Frank M. Raushel

  DOI：10.1016/s0960-894x(00)00213-4

  日期：2000.6

  The enzyme OPAA hydrolyzes p-nitrophenyl phosphotriesters bearing substituents at the phosphorus center ranging in size from methyl to phenyl. The enzyme exhibits stereoselectivity toward the hydrolysis of chiral substrates with a preference for the Sp enantiomer. (C) 2000 Elsevier Science Ltd. All rights reserved.