4-(meth)acryloyloxybutyl phosphate | 40074-59-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 4-(meth)acryloyloxybutyl phosphate
• 英文别名: 4-methacryloyloxybutyl dihydrogenphosphate；4-(Phosphonooxy)butyl 2-methylprop-2-enoate；4-phosphonooxybutyl 2-methylprop-2-enoate
• CAS: 40074-59-7
• 化学式: C₈H₁₅O₆P
• 分子量: 238.177
• InChiKey: GMCNAQYARMUGJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  93.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  甲基丙烯酸4-羟基丁酯 生成 4-(meth)acryloyloxybutyl phosphate
  参考文献：
  名称：

  Organophosphorus compounds for dental polymerizable compositions

  摘要：

  具有至少一个可自由基聚合双键，至少一个具有一个或两个羟基的磷酸残基，以及至少一个分子中含有4个或更多碳原子的烃基的有机磷酸化合物，其中该有机磷酸化合物的10%甲醇溶液在25°C时的电导率为0.5 mS/cm或更低，和/或该有机磷酸化合物在455 nm处的透光率为90%或更高；制备该有机磷酸化合物的方法；包括（a）该有机磷酸化合物和（b）能够与该有机磷酸化合物共聚的可聚合单体的牙科可聚合组合物。

  公开号：

  US06458868B1
• 作为试剂：
  描述：

  甲基丙烯酸4-羟基丁酯 、 、 、 6-methacryloyloxyhexyl phosphate 在 4-(meth)acryloyloxybutyl phosphate 作用下， 以to give 4-methacryloyloxybutyl dihydrogenphosphate (Compound 1e)的产率得到4-(meth)acryloyloxybutyl phosphate
  参考文献：
  名称：

  Organophosphorus compounds for dental polymerizable compositions

  摘要：

  一种有至少一个基团可自由基聚合的双键、至少一个磷酸残基具有一个或两个羟基、以及至少一个分子中含有4个或更多碳原子的碳氢基团的有机磷酸酯化合物，其中该有机磷酸酯化合物的10%重量甲醇溶液在25℃时的电导率为0.5 mS/cm或更低，和/或该有机磷酸酯化合物在455 nm处的光透过率为90%或更高；制备该有机磷酸酯化合物的方法；以及包括（a）该有机磷酸酯化合物和（b）能够与该有机磷酸酯化合物共聚合的可聚合单体的牙科可聚合组合物。

  公开号：

  US06458868B1

文献信息

• DENTAL CEMENT
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20170135909A1

  公开（公告）日：2017-05-18

  The present invention provides a dental cement that exhibits excellent adhesiveness to dentin and has high mechanical strength. The present invention relates to a multi-part dental cement containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); a hydrophobic crosslinkable polymerizable monomer (c); a chemical polymerization initiator (d); and a filler (e). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C 1 to C 6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR 1 —, —CO—NR 1 —, —NR 1 —CO—, —CO—O—NR 1 —, —O—CO—NR 1 —, and —NR 1 —CO—NR 1 —, and R 1 is a hydrogen atom or an optionally substituted, linear or branched C 1 to C 6 aliphatic group.

  本发明提供一种对牙本质具有良好粘附性并具有高机械强度的牙科水泥。本发明涉及一种含有多部分的牙科水泥，包括：一种不对称的丙烯酰胺-甲基丙烯酸酯化合物（a）；一种含酸基的（甲基）丙烯酸聚合单体（b）；一种疏水性交联聚合单体（c）；一种化学聚合引发剂（d）；和一种填料（e）。不对称的丙烯酰胺-甲基丙烯酸酯化合物（a）由以下一般式（1）表示：其中X是可选择取代的线性或支链的C1到C6脂肪族基团或可选择取代的芳香族基团，脂肪族基团可选择地被来自由—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—组成的至少一种连接基团中断，且R1是氢原子或可选择取代的线性或支链的C1到C6脂肪族基团。
• DENTAL ADHESIVE
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20170196778A1

  公开（公告）日：2017-07-13

  The present invention provides a dental adhesive exhibiting excellent initial bond strength and bond durability to both enamel and dentin. The present invention relates to a dental adhesive containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); and a water-soluble polymerizable monomer (c). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C 1 to C 6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR 1 —, —CO—NR 1 —, —NR 1 —CO—, —CO—O—NR 1 —, —O—CO—NR 1 —, and —NR 1 —CO—NR 1 —, and R 1 is a hydrogen atom or an optionally substituted, linear or branched C 1 to C 6 aliphatic group.

  本发明提供了一种牙科粘接剂，具有优异的初始粘接强度和对牙釉质和牙本质的粘接耐久性。本发明涉及一种含有以下成分的牙科粘接剂：不对称丙烯酰胺-甲基丙烯酸酯化合物（a）；含酸基的（甲基）丙烯酸聚合单体（b）；以及水溶性聚合单体（c）。不对称丙烯酰胺-甲基丙烯酸酯化合物（a）由下述一般式（1）表示：其中X是可选择取代的线性或支链状的C1到C6脂肪族基或可选择取代的芳香族基，所述脂肪族基可被来自由—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—组成的至少一个连接基中断，R1为氢原子或可选择取代的线性或支链状的C1到C6脂肪族基。
• SELF-ADHESIVE DENTAL COMPOSITE RESIN
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20170135910A1

  公开（公告）日：2017-05-18

  The present invention provides a self-adhesive composite resin having excellent adhesiveness to tooth structures and excellent mechanical strength. The present invention relates to a self-adhesive dental composite resin containing: an asymmetric acrylamide-methacrylic acid ester compound (a); an acid group-containing (meth)acrylic polymerizable monomer (b); a hydrophobic crosslinkable polymerizable monomer (c); a photopolymerization initiator (d); and a filler (e). The asymmetric acrylamide-methacrylic acid ester compound (a) is represented by the following general formula (1): where X is an optionally substituted, linear or branched C 1 to C 6 aliphatic group or an optionally substituted aromatic group, the aliphatic group is optionally interrupted by at least one linking group selected from the group consisting of —O—, —S—, —CO—, —CO—O—, —O—CO—, —NR 1 —, —CO—NR 1 —, —NR 1 —CO—, —CO—O—NR 1 —, —O—CO—NR 1 —, and —NR 1 —CO—NR 1 —, and R 1 is a hydrogen atom or an optionally substituted, linear or branched C 1 to C 6 aliphatic group.

  本发明提供了一种具有优异粘附性和优异机械强度的自粘合复合树脂。本发明涉及一种自粘合牙科复合树脂，包含：不对称的丙烯酰胺-甲基丙烯酸酯化合物（a）；含酸基的（甲基）丙烯酸聚合单体（b）；疏水性交联聚合单体（c）；光聚合引发剂（d）；和填料（e）。不对称的丙烯酰胺-甲基丙烯酸酯化合物（a）由以下通式（1）表示：其中X是可选取代的线性或支链的C1至C6脂肪族基团或可选取代的芳香族基团，脂肪族基团可由以下组成的至少一种连接基团中断：—O—、—S—、—CO—、—CO—O—、—O—CO—、—NR1—、—CO—NR1—、—NR1—CO—、—CO—O—NR1—、—O—CO—NR1—和—NR1—CO—NR1—，R1为氢原子或可选取代的线性或支链的C1至C6脂肪族基团。
• MULTI-PART DENTAL CEMENT
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US20190262240A1

  公开（公告）日：2019-08-29

  The present invention provides a dental cement showing excellent storage stability, undergoing little change in paste properties during long-term storage, and having a small solidification risk during long-term storage. The present invention relates to a multi-part dental cement comprising: a first paste comprising an acid group-containing (meth)acrylic polymerizable monomer (a), a polyfunctional (meth)acrylic polymerizable monomer (b) containing no acid group, an oxidizing agent (c-1) of a chemical polymerization initiator, and a filler (d); and a second paste comprising a polyfunctional (meth)acrylic polymerizable monomer (b) containing no acid group, a reducing agent (c-2) of a chemical polymerization initiator, and a filler (e), wherein the filler (d) is treated with a surface treatment agent and has an average particle diameter of 0.01 to 50.0 μm, the surface treatment agent comprises a silane coupling agent (A) represented by the general formula (1) and an organosilazane (B) represented by the general formula (2).

  本发明提供了一种牙科水泥，具有出色的储存稳定性，在长期储存期间，其糊剂性能变化很小，并且在长期储存期间固化风险较小。本发明涉及一种多部分牙科水泥，包括：第一糊剂，包括含有酸基的（甲基）丙烯酸聚合单体（a），不含酸基的多官能团（甲基）丙烯酸聚合单体（b），化学聚合引发剂的氧化剂（c-1），和填料（d）；以及第二糊剂，包括不含酸基的多官能团（甲基）丙烯酸聚合单体（b），化学聚合引发剂的还原剂（c-2），和填料（e），其中填料（d）经过表面处理剂处理，平均粒径为0.01至50.0μm，表面处理剂包括通式（1）表示的硅烷偶联剂（A）和通式（2）表示的有机硅氮烷（B）。
• Two paste-type glass ionomer cement
  申请人：Takano Satosi

  公开号：US20060247330A1

  公开（公告）日：2006-11-02

  An object of the present invention is to provide a paste-type cement composition which while retaining adhesion to tooth substance, biocompatibility, surface curability and fluorine sustained-releasability which are the characteristics derived from the conventional glass ionomer cement, reduces water sensitivity which is shortcoming of the conventional glass ionomer cement, enables simple mixing operation, does not adversely affect on the various properties of a cured cement depending on a difference in operators or a skill degree, and can afford various stable properties. There is provided a two paste-type glass ionomer cement comprising a resin-based paste containing a hydrophobic polymerizable monomer and a polymer of acidic group-containing polymerizable monomers which are insoluble to each other, and a water-based paste containing a hydrophilic polymerizable monomer and water which are soluble to each other, in which an acid reactive filler is contained in at least one of pastes.

  本发明的一个目的是提供一种浆糊型水泥组合物，该组合物在保持对牙齿物质的粘附性、生物相容性、表面可固化性和氟释放性这些传统玻璃离子水泥的特性的同时，减少了传统玻璃离子水泥的水敏感性这一缺点，实现了简单的混合操作，不会对已固化水泥的各种性质产生不利影响，不会受到操作者差异或技能水平的影响，并且可以提供各种稳定的性质。提供了一种双浆糊型玻璃离子水泥，包括一种含有疏水性可聚合单体和含有酸性基团可聚合单体聚合物的树脂基浆糊，这些单体在彼此之间不溶解，以及一种含有亲水性可聚合单体和水的水基浆糊，这些单体在彼此之间可溶解，其中至少有一个浆糊中含有酸反应填料。