fluorochlorothioacetyl fluoride | 814-84-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 硫代碳卤化物
• 英文名称: fluorochlorothioacetyl fluoride
• 英文别名: chlorofluorothioacetyl fluoride；Chlorfluorthioacetylfluorid；Acetyl fluoride, chlorofluorothio-；2-chloro-2-fluoroethanethioyl fluoride
• CAS: 814-84-6
• 化学式: C₂HClF₂S
• 分子量: 130.546
• InChiKey: LUIHJYLWXVDRNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  6
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  32.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氯-1,1,2-三氟乙硫醇 在 sodium fluoride 作用下， 生成 fluorochlorothioacetyl fluoride
  参考文献：
  名称：

  The Free Radical Addition of Hydrogen Sulfide to Fluoroethylenes

  摘要：

  DOI：

  10.1021/ja00889a022

文献信息

• Synthesis and reactivity of fluorine-containing thiols and thioacyl halides
  作者：A. Yu. Sizov、A. N. Kovregin、R. N. Serdyuk、M. V. Vorob’ev、V. A. Porosyatnikov、A. A. Tsvetkov、D. O. Korneev、A. F. Ermolov

  DOI：10.1007/s11172-006-0399-4

  日期：2006.7

  α-hydropolyfluoroalkanethiols and polyfluorothioacyl halides via thermal splitting of benzyl polyfluoroalkyl sulfides under the action of phosphorus pentoxide was proposed. The thiols obtained were used as starting materials for the synthesis of α-hydropolyfluoroalkanesulfenyl chlorides. The properties of the resulting F,S-containing compounds were studied.

  提出了在五氧化二磷作用下通过苄基多氟烷基硫化物的热裂解制备α-氢多氟烷硫醇和多氟硫酰卤的路线。获得的硫醇用作合成α-氢多氟烷亚磺酰氯的原料。研究了所得含 F,S 化合物的性质。
• Fluorine-containing ?-hydrothionyl fluorides
  作者：R. A. Bekker、V. Ya. Popkova

  DOI：10.1007/bf00961512

  日期：1990.8

  A method has been found for the synthesis of fluoride-containing alpha-hydrothionyl fluorides by heating polyfluoroalkenyl benzyl sulfides having fluoride atoms in the alpha-position relative to the sulfur atom with fluorosulfonic acid. The reactions of the acid fluorides obtained with secondary amines were studied. The reaction of the alpha-hydrotetrafluorothiopropionyl fluoride with NH(Me)2 leads to the amide of the corresponding acid, while the product of alpha-hydrohexafluorothioisobutyryl fluoride with diethylamine is the dimer of bis(trifluoromethyl) thioketene.
• BEKKER, R. A.;POPKOVA, V. YA.;KNUNYANTS, I. L.
  作者：BEKKER, R. A.、POPKOVA, V. YA.、KNUNYANTS, I. L.

  DOI：——

  日期：——
• BEKKER, R. A.;POPKOVA, V. YA., IZV. AN CCCP. CEP. XIM.,(1990) N, S. 1898-1901
  作者：BEKKER, R. A.、POPKOVA, V. YA.

  DOI：——

  日期：——