2-[2-[(2-Oxo-1,3,2lambda5-dioxaphospholan-2-yl)oxy]ethoxy]ethanol

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2-[2-[(2-Oxo-1,3,2lambda5-dioxaphospholan-2-yl)oxy]ethoxy]ethanol
• 英文别名: 2-[2-[(2-oxo-1,3,2λ5-dioxaphospholan-2-yl)oxy]ethoxy]ethanol
• 化学式: C₆H₁₃O₆P
• 分子量: 212.14
• InChiKey: RICOHFIGTUHODJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  74.2
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• HYPERBRANCHED AMINO ACID-BASED POLY(ESTER UREA)S FOR REGENERATIVE MEDICINE AND DRUG DELIVERY
  申请人：Becker Matthew

  公开号：US20160130390A1

  公开（公告）日：2016-05-12

  One or more embodiments of the present invention provide a hyperbranched amino-acid-based PEU polymer for use in regenerative medicine and/or drug delivery applications has tunable mechanical and thermal properties, but is sufficiently stable to permit such things as ethyloxide sterilization without degradation and/or significant loss of function. These hyperbranched amino acid-based poly(ester urea) (PEU) by interfacial polycondensation between linear and branched amino acid-based polyester monomers and a urea forming material such as trisphosgene or phosgene. By controlling the amount of branched monomer incorporated into the copolymer, the mechanical properties and water uptake abilities of the resulting hyperbranched amino acid-based PEUs may be tuned. The hyperbranched PEUs nanofibers are sterilizable with ETO and are stable for long periods of ETO sterilization, elevated temperature and exposure to aqueous environments. In various embodiments, these hyperbranched amino acid-based PEUs are also biodegradable and can be formed into fibers.
• US9745414B2
  申请人：——

  公开号：US9745414B2

  公开（公告）日：2017-08-29