Tris(1-adamantyl) phosphate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: Tris(1-adamantyl) phosphate
• 化学式: C₃₀H₄₅O₄P
• 分子量: 500.6
• InChiKey: GXPBQXXEWYYANV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  35
• 可旋转键数：
  6
• 环数：
  12.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Phosphorus compound
  申请人：——

  公开号：US20030109736A1

  公开（公告）日：2003-06-12

  The phosphorus-containing compound of the present invention is represented by the following formula (I), (II) or (III): 1 wherein Z 1 , Z 2 and Z 3 each represents a cycloalkane, a cycloalkene, a polycyclic aliphatic hydrocarbon or an aromatic hydrocarbon rings which may have a substituent; R represents a halogen atom, a hydroxyl, a carboxyl, a halocarboxyl (haloformyl), an alkyl, an alkoxy, an alkenyl or an aryl groups; A represents a polyvalent group corresponding to an alkane; Y 1 , Y 2 and Y 3 each represents —O—, —S— or —NR 1 —, wherein R 1 represents a hydrogen atom or an alkyl group; k is an integer of to 6; m is an integer of 0 to 2; n is an integer of not less than 1; q is an integer of 0 to 5; r is 0 or 1; and S is an integer of 1 to 4. The phosphorus-containing compound is excellent in heat resistance and is useful as flame retardants, plasticizers, or stabilizers.

  本发明的含磷化合物由以下式(I)、(II)或(III)表示：其中Z1、Z2和Z3分别表示可能具有取代基团的环烷烃、环烯烃、多环脂肪烃或芳香烃环；R表示卤素原子、羟基、羧基、卤代羧基（卤甲酰基）、烷基、烷氧基、烯基或芳基；A表示对应于烷烃的多价基团；Y1、Y2和Y3分别表示—O—、—S—或—NR1—，其中R1表示氢原子或烷基；k为0至6的整数；m为0至2的整数；n为不少于1的整数；q为0至5的整数；r为0或1；S为1至4的整数。这种含磷化合物具有优异的耐热性，可用作阻燃剂、增塑剂或稳定剂。
• PHOSPHORUS COMPOUND
  申请人：Daicel Chemical Industries, Ltd.

  公开号：EP1277758A1

  公开（公告）日：2003-01-22

  The phosphorus-containing compound of the present invention is represented by the following formula (I), (II) or (III):    wherein Z1, Z2 and Z3 each represents a cycloalkane, a cycloalkene, a polycyclic aliphatic hydrocarbon or an aromatic hydrocarbon rings which may have a substituent; R represents a halogen atom, a hydroxyl, a carboxyl, a halocarboxyl (haloformyl), an alkyl, an alkoxy, an alkenyl or an aryl groups; A represents a polyvalent group corresponding to an alkane; Y1, Y2 and Y3 each represents -O-, -S- or -NR1-, wherein R1 represents a hydrogen atom or an alkyl group; k is an integer of 1 to 6; m is an integer of 0 to 2; n is an integer of not less than 1; q is an integer of 0 to 5; r is 0 or 1; and s is an integer of 1 to 4. The phosphorus-containing compound is excellent in heat resistance and is useful as flame retardants, plasticizers, or stabilizers.

  本发明的含磷化合物由下式（I）、（II）或（III）表示： 其中，Z1、Z2 和 Z3 分别代表环烷、环烯、多环脂肪烃或芳香烃环，这些环可能具有取代基；R 代表卤素原子、羟基、羧基、卤代烃基（卤代甲酰基）、烷基、烷氧基、烯基或芳基；A代表对应于烷烃的多价基团；Y1、Y2 和 Y3 各自代表-O-、-S- 或-NR1-，其中 R1 代表氢原子或烷基；k 是 1 至 6 的整数；m 是 0 至 2 的整数；n 是不小于 1 的整数；q 是 0 至 5 的整数；r 是 0 或 1；以及 s 是 1 至 4 的整数。 含磷化合物具有优异的耐热性，可用作阻燃剂、增塑剂或稳定剂。
• DETERMINATION OF NUCLEASE ACTIVITY
  申请人：Zetatronics Limited

  公开号：EP1155143A1

  公开（公告）日：2001-11-21
• US6794528B2
  申请人：——

  公开号：US6794528B2

  公开（公告）日：2004-09-21
• [EN] DETERMINATION OF NUCLEASE ACTIVITY<br/>[FR] DETERMINATION DE L'ACTIVITE DE NUCLEASE
  申请人：HARBRON STUART

  公开号：WO2000049172A1

  公开（公告）日：2000-08-24

  A method for detecting a nuclease enzyme is disclosed which comprises a method for detecting a nuclease enzyme comprising the steps: a) contacting said enzyme with a compound of formula RpX, wherein R is a 3' nucleosidyl derivative, p is a phospho radical, and X is an esterifiable moiety or, only if R is a 3' nicotinamide derivative, X is an esterifiable moiety or H, whereby ROH and pX are produced, and b) detecting said pX moiety or, only if R is a 3' nicotinamide derivative, detecting the pX moiety or the ROH moiety. In preferred embodiments the invention provides a method for detecting a nuclease enzyme that is free in solution, immobilised on a surface, or attached to a member of a specific binding pair. The method of the invention may thus be applied as a detection step in nucleic acid hybridisation assays, enzyme immunoassays and ligand:receptor binding assays. The invention provides a variety of methods for detecting the detectable moieties produced. These include fluorometric, colorimetric, and luminometric endpoints. Enzyme cycling and apoenzyme reactivation assays are also provided.