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    首页 分子通 5-(4-ethoxyphenyl)-4-(3-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one

    5-(4-ethoxyphenyl)-4-(3-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one

    分子结构分类

    有机化合物 - 有机杂环化合物 - 吡咯并吡唑类
    中文名称
    ——
    中文别名
    ——
    英文名称
    5-(4-ethoxyphenyl)-4-(3-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one
    英文别名
    5-(4-ethoxyphenyl)-4-(3-fluorophenyl)-3-thiophen-2-yl-2,4-dihydropyrrolo[3,4-c]pyrazol-6-one
    5-(4-ethoxyphenyl)-4-(3-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one化学式
    CAS
    ——
    化学式
    C23H18FN3O2S
    mdl
    ——
    分子量
    419.5
    InChiKey
    UAJABHSREIUHFZ-UHFFFAOYSA-N
    BEILSTEIN
    ——
    EINECS
    ——
    • 物化性质
    • 计算性质
    • ADMET
    • 安全信息
    • SDS
    • 制备方法与用途
    • 上下游信息
    • 反应信息
    • 文献信息
    • 表征谱图
    • 同类化合物
    • 相关功能分类
    • 相关结构分类

    计算性质

    • 辛醇/水分配系数(LogP)：
      4.7
    • 重原子数：
      30
    • 可旋转键数：
      5
    • 环数：
      5.0
    • sp3杂化的碳原子比例：
      0.13
    • 拓扑面积：
      86.5
    • 氢给体数：
      1
    • 氢受体数：
      5

    文献信息

    • ANTI-FLAVIVIRUS COMPOUNDS AND METHODS OF USE
      申请人：FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
      公开号：US20200197369A1
      公开（公告）日：2020-06-25
      The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
    • METHOD FOR INHIBITING ZIKA VIRUS INFECTION
      申请人：FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
      公开号：US20220323420A1
      公开（公告）日：2022-10-13
      The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
    查看更多

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