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    —— methyl (3R)-5-bromo-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C17H16BrClN4O3S
    methyl (3R)-5-bromo-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((5-((4-amino-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H24ClN5O4S2
    methyl 1-((5-((4-amino-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 4-((2-(1'-acetyl-5-chlorospiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)thiazol-5-yl)oxy)-2-fluorobenzoate —— C25H22ClFN4O5S
    methyl 4-((2-(1'-acetyl-5-chlorospiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)thiazol-5-yl)oxy)-2-fluorobenzoate
    —— methyl 5-chloro-1-((4-methylthiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C18H19ClN4O3S
    methyl 5-chloro-1-((4-methylthiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((4-(2-amino-2-oxoethyl)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C19H20ClN5O4S
    methyl 1-((4-(2-amino-2-oxoethyl)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((4-(2-(dimethylamino)-2-oxoethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H24ClN5O4S
    methyl 5-chloro-1-((4-(2-(dimethylamino)-2-oxoethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-(3-ethoxy-3-oxopropyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H25ClN4O5S
    methyl 5-chloro-1-((5-(3-ethoxy-3-oxopropyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (3S)-5,6-dichloro-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C17H15Cl3N4O3S
    methyl (3S)-5,6-dichloro-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((5-((4-(azetidin-1-yl)-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C24H28ClN5O4S2
    methyl 1-((5-((4-(azetidin-1-yl)-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-(piperidine-1-carbonyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C23H26ClN5O4S
    methyl 5-chloro-1-((5-(piperidine-1-carbonyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((4-(3-(dimethylamino)-3-oxopropyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H26ClN5O4S
    methyl 5-chloro-1-((4-(3-(dimethylamino)-3-oxopropyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((4-(piperidin-1-ylmethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C23H28ClN5O3S
    methyl 5-chloro-1-((4-(piperidin-1-ylmethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-(2-hydroxyethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C19H21ClN4O4S
    methyl 5-chloro-1-((5-(2-hydroxyethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C20H17ClF6N4O4S
    methyl 5-chloro-1-((5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 6-(1'-acetyl-5-(N-benzyl-N-methylsulfamoyl)spiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)nicotinate —— C29H31N5O6S
    methyl 6-(1'-acetyl-5-(N-benzyl-N-methylsulfamoyl)spiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)nicotinate
    —— methyl 5-((2-(1'-acetyl-5-chlorospiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)thiazol-5-yl)oxy)nicotinate —— C24H22ClN5O5S
    methyl 5-((2-(1'-acetyl-5-chlorospiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)thiazol-5-yl)oxy)nicotinate
    —— methyl 5-chloro-1-((5-((2-methoxy-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C20H21ClN4O5S2
    methyl 5-chloro-1-((5-((2-methoxy-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((4-(hydroxyamino)-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H24ClN5O5S2
    methyl 5-chloro-1-((5-((4-(hydroxyamino)-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C24H29ClN4O5S2
    methyl 5-chloro-1-((5-((2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C17H16Cl2N4O3S
    methyl 5-chloro-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-(pyrrolidine-1-carbonyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H24ClN5O4S
    methyl 5-chloro-1-((5-(pyrrolidine-1-carbonyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((5-((2-aminoethyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C19H22ClN5O3S2
    methyl 1-((5-((2-aminoethyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((5-((3-aminopropyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C20H24ClN5O3S2
    methyl 1-((5-((3-aminopropyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((4-(3-amino-3-oxopropyl)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C20H22ClN5O4S
    methyl 1-((4-(3-amino-3-oxopropyl)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((3-(dimethylamino)-3-oxopropyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H26ClN5O4S2
    methyl 5-chloro-1-((5-((3-(dimethylamino)-3-oxopropyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((1-ethoxy-1-oxobutan-2-yl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C23H27ClN4O5S2
    methyl 5-chloro-1-((5-((1-ethoxy-1-oxobutan-2-yl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((3-(dimethylamino)propyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H28ClN5O3S2
    methyl 5-chloro-1-((5-((3-(dimethylamino)propyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (2R)-3-hydroxy-2-[[1-[[(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-yl]carbamoyl]cyclopentanecarbonyl]amino]propanoate —— C15H24N2O8
    methyl (2R)-3-hydroxy-2-[[1-[[(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-yl]carbamoyl]cyclopentanecarbonyl]amino]propanoate
    —— methyl 5,6-dibromo-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C17H15Br2ClN4O3S
    methyl 5,6-dibromo-1-((5-chlorothiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (2R)-3-hydroxy-2-[[1-[[(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-yl]carbamoyl]cyclobutanecarbonyl]amino]propanoate —— C14H22N2O8
    methyl (2R)-3-hydroxy-2-[[1-[[(2R)-3-hydroxy-1-methoxy-1-oxopropan-2-yl]carbamoyl]cyclobutanecarbonyl]amino]propanoate
    —— methyl 5-chloro-1-((4-(3-ethoxy-3-oxopropyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H25ClN4O5S
    methyl 5-chloro-1-((4-(3-ethoxy-3-oxopropyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-(4-(dimethylamino)-4-oxobutyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C23H28ClN5O4S
    methyl 5-chloro-1-((5-(4-(dimethylamino)-4-oxobutyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 6-(1'-acetyl-5-((4-methylpiperazin-1-yl)sulfonyl)spiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)nicotinate —— C26H32N6O6S
    methyl 6-(1'-acetyl-5-((4-methylpiperazin-1-yl)sulfonyl)spiro[indoline-3,3'-pyrrolidin]-1-ylcarboxamido)nicotinate
    —— methyl 5-chloro-1-((5-((3-methoxypropyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H25ClN4O4S2
    methyl 5-chloro-1-((5-((3-methoxypropyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((2-(methylamino)-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C20H22ClN5O4S2
    methyl 5-chloro-1-((5-((2-(methylamino)-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-((3-((methoxycarbonyl)amino)propyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C22H26ClN5O5S2
    methyl 5-chloro-1-((5-((3-((methoxycarbonyl)amino)propyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (3R)-5-bromo-1-((5-((2-ethoxy-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H23BrN4O5S2
    methyl (3R)-5-bromo-1-((5-((2-ethoxy-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (3S)-5-(N-benzyl-N-(2-(dimethylamino)ethyl)sulfamoyl)-1-((5-methoxythiazolo[5,4-b]pyridin-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C32H37N7O6S2
    methyl (3S)-5-(N-benzyl-N-(2-(dimethylamino)ethyl)sulfamoyl)-1-((5-methoxythiazolo[5,4-b]pyridin-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 5-chloro-1-((5-methoxythiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C18H19ClN4O4S
    methyl 5-chloro-1-((5-methoxythiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— Methyl 3-(2-amino-1,3-thiazol-5-yl)benzoate —— C11H10N2O2S
    Methyl 3-(2-amino-1,3-thiazol-5-yl)benzoate
    —— methyl 5-chloro-1-((5-((4-(dimethylamino)-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C23H28ClN5O4S2
    methyl 5-chloro-1-((5-((4-(dimethylamino)-4-oxobutyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (S)-1-((5-((3-(t-butoxy)-3-oxopropyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C24H29ClN4O5S2
    methyl (S)-1-((5-((3-(t-butoxy)-3-oxopropyl)thio)thiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (3R)-5-(N-benzyl-N-(2-hydroxyethyl)sulfamoyl)-1-((5-methoxythiazolo[5,4-b]pyridin-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C30H32N6O7S2
    methyl (3R)-5-(N-benzyl-N-(2-hydroxyethyl)sulfamoyl)-1-((5-methoxythiazolo[5,4-b]pyridin-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl 1-((4-butylthiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H25ClN4O3S
    methyl 1-((4-butylthiazol-2-yl)carbamoyl)-5-chlorospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (3S)-5-chloro-1-((5-methylthiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C18H19ClN4O3S
    methyl (3S)-5-chloro-1-((5-methylthiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (3S)-2-[(4-morpholin-4-ylsulfonylphenyl)carbamothioyl]-3,4-dihydro-1H-isoquinoline-3-carboxylate —— C22H25N3O5S2
    methyl (3S)-2-[(4-morpholin-4-ylsulfonylphenyl)carbamothioyl]-3,4-dihydro-1H-isoquinoline-3-carboxylate
    —— methyl 5-bromo-1-((5-((2-ethoxy-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C21H23BrN4O5S2
    methyl 5-bromo-1-((5-((2-ethoxy-2-oxoethyl)thio)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— Methyl 4-[[5-[[4-(2-oxopyrrolidin-1-yl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]sulfanylmethyl]benzoate —— C22H20N4O4S2
    Methyl 4-[[5-[[4-(2-oxopyrrolidin-1-yl)benzoyl]amino]-1,3,4-thiadiazol-2-yl]sulfanylmethyl]benzoate
    —— methyl 5-chloro-1-((4-(hydroxymethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate —— C18H19ClN4O4S
    methyl 5-chloro-1-((4-(hydroxymethyl)thiazol-2-yl)carbamoyl)spiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
    —— methyl (4R,5R)-4-[5-(3-chlorophenyl)furan-2-yl]-6-methylidene-2-sulfanylidene-1,3-diazinane-5-carboxylate —— C17H15ClN2O3S
    methyl (4R,5R)-4-[5-(3-chlorophenyl)furan-2-yl]-6-methylidene-2-sulfanylidene-1,3-diazinane-5-carboxylate