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    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C31H36F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(4-hydroxyoxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C31H35F2N7O4
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(4-hydroxyoxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C30H35F2N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-hydroxyoxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C30H34F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-hydroxyoxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C31H35F3N8O2
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[4-(4-cyanooxan-4-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C32H34F2N8O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[4-(4-cyanooxan-4-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(2-cyanopropan-2-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C29H31F2N9O2
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(2-cyanopropan-2-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C31H36F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C31H34F3N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C30H36F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethoxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C28H32F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethoxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C32H38F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(4-cyclopropyl-2,6-difluorophenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C29H32F2N8O2
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(4-cyclopropyl-2,6-difluorophenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C27H30F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C27H30F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C28H32F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C29H34F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-methoxyethoxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C29H34F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C30H33F3N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-3-(propan-2-ylcarbamoyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C30H35F2N9O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-3-(propan-2-ylcarbamoyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C30H33F3N8O2
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C28H30F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C29H34F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C29H34F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-methoxycyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C31H36F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-methoxycyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C28H32F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-hydroxyoxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C28H30F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-hydroxyoxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C29H32F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[4-(4-cyanooxan-4-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C33H36F2N8O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[4-(4-cyanooxan-4-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl (2-bromo-4-{(E)-[1-(3,4-dimethylphenyl)-2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene]methyl}phenoxy)acetate —— C22H19BrN2O6
    methyl (2-bromo-4-{(E)-[1-(3,4-dimethylphenyl)-2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene]methyl}phenoxy)acetate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methylphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C26H28F2N8O2
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methylphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[4-(2-cyanopropan-2-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C31H34F2N8O2
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[4-(2-cyanopropan-2-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C26H28F2N8O4S
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-fluorooxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C28H29F3N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-fluorooxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C31H37F2N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(propan-2-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C28H32F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C30H34F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C29H33F2N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C28H31F2N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methoxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C26H28F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methoxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C33H39F2N7O4
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(4-cyclopropyl-2,6-difluorophenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C28H30F2N8O2
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(4-cyclopropyl-2,6-difluorophenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-(4-cyclopropyl-2,6-difluorophenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C30H33F2N7O2
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-(4-cyclopropyl-2,6-difluorophenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-[(2-oxopyrrolidin-1-yl)methyl]phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C30H33F2N9O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-[(2-oxopyrrolidin-1-yl)methyl]phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C32H37F2N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C30H33F2N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-3-(propan-2-ylcarbamoyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C29H33F2N9O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-3-(propan-2-ylcarbamoyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— methyl N-[(1S,2R,6S)-2-amino-4-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C30H35F2N7O3
    methyl N-[(1S,2R,6S)-2-amino-4-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(3-fluorooxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C30H32F3N7O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(3-fluorooxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-oxocyclohexa-2,5-dien-1-ylidene)-1H-imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C25H26F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-oxocyclohexa-2,5-dien-1-ylidene)-1H-imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate