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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 苯并恶嗪类

    苯并恶嗪类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 7-bromo-4-(piperidin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one —— C14H16BrN3O2
    7-bromo-4-(piperidin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one
    —— N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}cyclopropanesulfonamide —— C26H28N6O4S
    N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}cyclopropanesulfonamide
    —— 7-(3,5-dimethylisoxazol-4-yl)-N-methyl-2-oxo-4-(pyridin-2-yl)-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-4-carboxamide 2,2,2-trifluoroacetate —— C2HF3O2*C21H19N5O4
    7-(3,5-dimethylisoxazol-4-yl)-N-methyl-2-oxo-4-(pyridin-2-yl)-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-4-carboxamide 2,2,2-trifluoroacetate
    —— (3S)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]-N-methylpyrrolidin-3-amine —— C24H26N6O2
    (3S)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]-N-methylpyrrolidin-3-amine
    —— 4-[(11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid —— C25H23N5O4
    4-[(11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid
    —— 2-{[7-(3,5-dimethylisoxazol-4-yl)-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]amino}ethanol —— C22H22N4O3
    2-{[7-(3,5-dimethylisoxazol-4-yl)-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]amino}ethanol
    —— 4-[(11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-2-yl]-1,4-diazepane-1-carboxylic acid —— C25H26N6O4
    4-[(11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-2-yl]-1,4-diazepane-1-carboxylic acid
    —— 3-[7-(3,5-dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazin-4-yl]-N,N-dimethylpyridine-2-carboxamide —— C22H21N5O4
    3-[7-(3,5-dimethylisoxazol-4-yl)-2-oxo-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazin-4-yl]-N,N-dimethylpyridine-2-carboxamide
    —— 7-bromo-4-ethyl-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one —— C16H14BrN3O2
    7-bromo-4-ethyl-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one
    —— N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}-2-methoxy-N-methylacetamide —— C27H30N6O4
    N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}-2-methoxy-N-methylacetamide
    —— 7-(3,5-dimethylisoxazol-4-yl)-N-methyl-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-amine —— C21H20N4O2
    7-(3,5-dimethylisoxazol-4-yl)-N-methyl-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-amine
    —— 7-(3,5-dimethylisoxazol-4-yl)-N-(2-hydroxyethyl)-2-oxo-4-phenyl-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-5-carboxamide —— C23H22N4O5
    7-(3,5-dimethylisoxazol-4-yl)-N-(2-hydroxyethyl)-2-oxo-4-phenyl-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-5-carboxamide
    —— 7-nitro-1a-pyridin-2-yl-1a,2-dihydro-1H-azireno[2,1-c][1,4]benzoxazine —— C14H11N3O3
    7-nitro-1a-pyridin-2-yl-1a,2-dihydro-1H-azireno[2,1-c][1,4]benzoxazine
    —— 4-[2-(aminomethyl)pyridin-3-yl]-7-(3,5-dimethylisoxazol-4-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one bis(trifluoroacetate) —— C24H21F6N5O7
    4-[2-(aminomethyl)pyridin-3-yl]-7-(3,5-dimethylisoxazol-4-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one bis(trifluoroacetate)
    —— US9624241, Example 77 —— C20H17N5O4
    US9624241, Example 77
    —— 7-(3,5-dimethyl-1,2-oxazol-4-yl)-N-methyl-2-oxo-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-triene-10-carboxamide;2,2,2-trifluoroacetic acid —— C23H20F3N5O6
    7-(3,5-dimethyl-1,2-oxazol-4-yl)-N-methyl-2-oxo-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-triene-10-carboxamide;2,2,2-trifluoroacetic acid
    —— (3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]-N,N-dimethylpyrrolidin-3-amine —— C25H28N6O2
    (3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]-N,N-dimethylpyrrolidin-3-amine
    —— US9624241, Example 200 —— C21H22N6O2
    US9624241, Example 200
    —— 7-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-oxo-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-triene-10-carboxamide;2,2,2-trifluoroacetic acid —— C22H18F3N5O6
    7-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-oxo-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-triene-10-carboxamide;2,2,2-trifluoroacetic acid
    —— 1-[7-(3,5-dimethylisoxazol-4-yl)-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-ol —— C24H24N4O3
    1-[7-(3,5-dimethylisoxazol-4-yl)-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-ol
    —— N'-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}-N,N-dimethylurea —— C26H29N7O3
    N'-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}-N,N-dimethylurea
    —— (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-(morpholin-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C23H23N5O3
    (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-(morpholin-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— 4-cyclohexyl-7-(3,5-dimethylisoxazol-4-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one —— C20H23N3O3
    4-cyclohexyl-7-(3,5-dimethylisoxazol-4-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one
    —— 7-(3,5-dimethylisoxazol-4-yl)-4-[1-(methylsulfonyl)piperidin-2-yl]-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one —— C20H24N4O5S
    7-(3,5-dimethylisoxazol-4-yl)-4-[1-(methylsulfonyl)piperidin-2-yl]-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one
    —— US9624241, Example 74 —— C20H17N5O4
    US9624241, Example 74
    —— 7-(3,5-dimethylisoxazol-4-yl)-4-(5-fluoropyridin-3-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one —— C19H15FN4O3
    7-(3,5-dimethylisoxazol-4-yl)-4-(5-fluoropyridin-3-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one
    —— 10-Pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-5-carbonitrile —— C15H12N4O
    10-Pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-5-carbonitrile
    —— 7-(3,5-dimethylisoxazol-4-yl)-2-(morpholin-4-yl)-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C24H24N4O3
    7-(3,5-dimethylisoxazol-4-yl)-2-(morpholin-4-yl)-4-phenyl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]piperidin-4-yl}acetamide —— C26H28N6O3
    N-{1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]piperidin-4-yl}acetamide
    —— N-{[2-oxo-4-(pyridin-2-yl)-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazin-4-yl]methyl}acetamide —— C17H16N4O3
    N-{[2-oxo-4-(pyridin-2-yl)-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazin-4-yl]methyl}acetamide
    —— 7-(3,5-dimethylisoxazol-4-yl)-N-methyl-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-amine —— C20H19N5O2
    7-(3,5-dimethylisoxazol-4-yl)-N-methyl-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-amine
    —— N-methyl-2-oxo-4-(pyridin-2-yl)-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-4-carboxamide —— C16H14N4O3
    N-methyl-2-oxo-4-(pyridin-2-yl)-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-4-carboxamide
    —— N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}methanesulfonamide —— C24H26N6O4S
    N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}methanesulfonamide
    —— 7-(3,5-dimethylisoxazol-4-yl)-2-oxo-4-phenyl-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-9-carbonitrile —— C21H16N4O3
    7-(3,5-dimethylisoxazol-4-yl)-2-oxo-4-phenyl-1,2,4,5-tetrahydroimidazo[1,5,4-de][1,4]benzoxazine-9-carbonitrile
    —— (4S)-9-{[(2,4-Dimethoxybenzyl)amino]methyl}-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one —— C29H29N5O5
    (4S)-9-{[(2,4-Dimethoxybenzyl)amino]methyl}-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one
    —— N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}propanamide —— C26H28N6O3
    N-{(3R)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]pyrrolidin-3-yl}propanamide
    —— US9624241, Example 140 —— C23H23N5O5
    US9624241, Example 140
    —— 7-(3,5-dimethylisoxazol-4-yl)-4-ethyl-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one 2,2,2-trifluoroacetate —— C2HF3O2*C21H20N4O3
    7-(3,5-dimethylisoxazol-4-yl)-4-ethyl-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one 2,2,2-trifluoroacetate
    —— (4S)-2-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C26H25N5O3
    (4S)-2-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— US9624241, Example 76 —— C21H19N5O4
    US9624241, Example 76
    —— 5-[(11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid —— C25H23N5O4
    5-[(11S)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-pyridin-2-yl-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-2-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid
    —— (4S)-2-(azetidin-1-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C22H21N5O2
    (4S)-2-(azetidin-1-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— 8-(3-Methoxyphenyl)-11-[(4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl)methylamino]-3,4,8,10,12-pentazatricyclo[7.4.0.02,6]trideca-1(13),2(6),4,9,11-pentaen-7-one —— C25H23N7O3
    8-(3-Methoxyphenyl)-11-[(4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl)methylamino]-3,4,8,10,12-pentazatricyclo[7.4.0.02,6]trideca-1(13),2(6),4,9,11-pentaen-7-one
    —— (4S)-9-(Aminomethyl)-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one bis(trifluoroacetate) —— C24H21F6N5O7
    (4S)-9-(Aminomethyl)-7-(3,5-dimethylisoxazol-4-yl)-4-pyridin-2-yl-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2(1H)-one bis(trifluoroacetate)
    —— (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[1-(methylsulfonyl)pyrrolidin-3-yl]-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C24H25N5O4S
    (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-[1-(methylsulfonyl)pyrrolidin-3-yl]-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-(4-propionyl-1,4-diazepan-1-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C27H30N6O3
    (4S)-7-(3,5-dimethylisoxazol-4-yl)-2-(4-propionyl-1,4-diazepan-1-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— US9624241, Example 168B —— C23H23N5O3
    US9624241, Example 168B
    —— (4S)-2-(4-acetyl-1,4-diazepan-1-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine —— C26H28N6O3
    (4S)-2-(4-acetyl-1,4-diazepan-1-yl)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazine
    —— Carbanide;7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-(1-oxidopyridin-1-ium-2-yl)-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-trien-2-one;trioxorhenium —— C20H19N4O7Re-
    Carbanide;7-(3,5-dimethyl-1,2-oxazol-4-yl)-11-(1-oxidopyridin-1-ium-2-yl)-9-oxa-1,3-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-trien-2-one;trioxorhenium
    —— (3S)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]piperidin-3-ol —— C24H25N5O3
    (3S)-1-[(4S)-7-(3,5-dimethylisoxazol-4-yl)-4-(pyridin-2-yl)-4,5-dihydroimidazo[1,5,4-de][1,4]benzoxazin-2-yl]piperidin-3-ol