申请人:Jame Fine Chemicals, Inc.
公开号:US05902801A1
公开(公告)日:1999-05-11
Glucosamine compositions comprising the compounds glucosamine sulfate metal chloride, wherein the metal, i.e. the cation, is lithium, sodium, magnesium, zinc or manganese. The compounds have purity levels of at least about 97%, with water present in a maximum amount of about 10 wt. %, based on the weight of the composition. The compounds are prepared by contacting glucosamine hydrochloride with the metal sulfate in the presence of water to form an aqueous solution of glucosamine sulfate metal chloride and thereafter freeze-drying the solution at a temperature and at a reduced pressure for such period of time that at least about 90 wt. % of the water is removed and decomposition of the compound glucosamine sulfate metal chloride is limited to a maximum of about 3%.
含有葡萄糖胺硫酸盐金属氯化物的葡萄糖胺组合物,其中金属即阳离子为锂、钠、镁、锌或锰。该化合物的纯度水平至少为约97%,水含量最多为约10重量%,基于该组合物的重量。该化合物是通过将葡萄糖胺盐酸盐与金属硫酸盐在水的存在下接触,形成葡萄糖胺硫酸盐金属氯化物的水溶液,然后在温度和减压下冷冻干燥一段时间,以使水的重量至少去除约90重量%,并将葡萄糖胺硫酸盐金属氯化物的分解限制在最多约3%。