| 1309388-30-4

• CAS: 1309388-30-4
• 化学式: C₃₀H₂₀FeN₂O₄
• 分子量: 528.347
• InChiKey: JOECDGGFTJZHJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  、 二甲羟胺盐酸盐 在 [benzotriazol-1-yloxytris(Me₂N)phosphonio]PF₆ 、 triethylamine 作用下， 以 二甲基亚砜 为溶剂， 以68.7%的产率得到
  参考文献：
  名称：

  Reaction of acetyl- and 1,1′-diacetylferrocene with isatin (Pfitzinger reaction)

  摘要：

  An efficient method for the synthesis of 2-ferrocenyl-substituted quinoline-4-carboxylic acids via the reaction of acetyl- and 1,1'-diacetylferrocene with isatin under the conditions of the Pfitzinger reaction was developed. Starting from the obtained acids methyl esters, amides, N-methyl-N-methoxyamides, and oximes (at one of the free acetyl groups) of some of these compounds were synthesized.

  DOI：

  10.1134/s1070363211030157
• 作为产物：
  描述：

  1,1'-di(4-carboxylatoquinolin-2-yl)ferrocenylene dipotassium salt 、 溶剂黄146 以 甲醇 为溶剂， 以84.2%的产率得到
  参考文献：
  名称：

  Reaction of acetyl- and 1,1′-diacetylferrocene with isatin (Pfitzinger reaction)

  摘要：

  An efficient method for the synthesis of 2-ferrocenyl-substituted quinoline-4-carboxylic acids via the reaction of acetyl- and 1,1'-diacetylferrocene with isatin under the conditions of the Pfitzinger reaction was developed. Starting from the obtained acids methyl esters, amides, N-methyl-N-methoxyamides, and oximes (at one of the free acetyl groups) of some of these compounds were synthesized.

  DOI：

  10.1134/s1070363211030157