Pd{1,1'-bis(diphenylphosphino)ferrocene}I2 | 124268-94-6

• 英文名称: Pd{1,1'-bis(diphenylphosphino)ferrocene}I2
• 英文别名: [(dppfc)PdI2]
• CAS: 124268-94-6
• 化学式: C₃₄H₂₈FeI₂P₂Pd
• 分子量: 914.62
• InChiKey: YPGVKLLKBWSPDE-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  Pd{1,1'-bis(diphenylphosphino)ferrocene}I2 、 E-2`-bromo-4-methoxyphenyl-(2`-(13)C)ethene 、 dilithio (cyclo-octatetraenide) 、 2-Methoxyphenylmagnesium bromide 以 四氢呋喃 为溶剂， 生成 (1,1`-bis(diphenylphosphino)ferrocene)Pd(p-OMeC6H4CHCH)I 、
  参考文献：
  名称：

  在钯催化的交叉偶联反应中绘制反应路径

  摘要：

  DOI：

  10.1021/om00116a010
• 作为产物：
  描述：

  1,1'-双(二苯基膦)二茂铁 、 dichloro(cycloocta-1,5-diene)palladium (II) 、 sodium iodide 以 丙酮 为溶剂， 以96%的产率得到Pd{1,1'-bis(diphenylphosphino)ferrocene}I2
  参考文献：
  名称：

  Synthesis, X-ray, spectroscopic and a preliminary Suzuki coupling screening studies of a complete series of dppfMX2 (M=Pt, Pd; X=Cl, Br, I)

  摘要：

  A complete series of dppfMX(2) (M = Pt, Pd; X = Cl, Br, I) compounds have been synthesized using different routes, and characterized fully. The synthesis of dppfPdI, has been achieved by reacting Pd(COD)Cl-2 with dppf in the presence of NaI. X-ray structures of dppfPdBr(2) and dppfPdI(2) have also been reported for the first time in this study. A preliminary Suzuki coupling screening study reveals that dppfPdX(2), compounds are superior to the conventional Ph3P-based catalysts and bidentate phosphine-based ligands. Reactions carried out under in situ conditions also gave a similar trend, but their respective activities were much lower than that of the fully formed catalysts. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)00981-0

文献信息

• Synthesis of Hemilabile Phosphine−Phosphine Oxide Ligands via the Highly Selective Pd-Catalyzed Mono-oxidation of Bidentate Phosphines:  Scope, Limitations, and Mechanism
  作者：Vladimir V. Grushin

  DOI：10.1021/om010454k

  日期：2001.9.1

  The first simple and efficient, one-step catalytic method has been developed for the preparation of bis-phosphine monoxides, valuable hemilabile ligands that have proven usefulness in homogeneous catalysis, synthesis, analytical chemistry, cancer and AIDS research, chemistry of materials, etc. Readily available bidentate phosphines (dppm, dppe, dppp, dppb, dppbz, dppfc, and BINAP) are selectively oxidized

  已经开发出了第一种简单有效的一步催化方法，用于制备一氧化二膦，有价值的半不稳定配体，这些配体已证明在均相催化，合成，分析化学，癌症和艾滋病研究，材料化学等方面有用。随时可用的二齿膦（dppm，dppe，dppp，dppb，dppbz，dppfc和BINAP）在存在碱和催化量的情况下，用1,2-二溴乙烷以65-90％的分离产率选择性氧化为相应的一氧化物。 （0.15-2 MOl％）的Pd（II）盐。这种厌氧氧化在20-80°C和大气压下的双相条件下平稳发生。在某些情况下，单氧化是由我提拔了-。新工艺的化学计量研究表明，催化环涉及（i）相应双膦的Pd（II）配合物与碱反应后形成Pd（0）和一氧化二膦（BPMO），（ ii）螯合驱动的膦配体交换以置换所产生的配位BPMO，以及（iii）P-d（0）配合物通过1,2-二溴乙烷经C-Br氧化加成再氧化，然后消除β-溴化物而再氧化。