cis-[Pd(NH3)2(H2O)2](2+) | 105698-19-9

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 过渡金属有机体
• 英文名称: cis-[Pd(NH3)2(H2O)2](2+)
• CAS: 105698-19-9；105814-30-0
• 化学式: H₁₀N₂O₂Pd
• 分子量: 176.512
• InChiKey: RJCUWNCWMXGMOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  水 、 cis-dichlorodiamminepalladium(II) 在 silver tetrafluoroborate 作用下， 以 水 为溶剂， 生成 cis-[Pd(NH3)2(H2O)2](2+)
  参考文献：
  名称：

  Interaction of Palladium(II) and Platinum(II) Complexes with Microperoxidase-11 Studied by Electrospray Mass Spectrometry and MS/MS Analysis

  摘要：

  Interactions of cis-[Pd(en)(H2O)(2)](2+) (en, ethylenediamine) and cis-[Pt(NH3)(2)(H2O)(2)](2+) with microperoxidase-11 (MP-11) in a molar ratio of 1:1 or 2:1 at pH 1.4 were investigated via electrospray mass spectrometry and MS/MS analysis at room temperature and at 40 degreesC with an incubation time of 2 or 3 days. The composition of the Pd(II)- and Pt(II)-anchored MP-11 was confirmed on the basis of the precise molecular mass and the simulated isotope distribution pattern. MS/MS analysis revealed that the Pd(II) center anchored to the side chain of Cys7 as Pd(II) and MP-11 were mixed in an equimolar ratio and to side chains of Cys7 and Cys4 as Pd(II) and MP-11 mixed in a 2:1 molar ratio. When Pt(II) and MP-11 were mixed in a 2:1 molar ratio, Pt(II) first anchored to the side chain of Cys7, and then to the side chain of Cys4 with time. The initial coordination of Pd(II) and Pt(II) to the side chain of Cys7 is the essential step for the Pd(II)- and Pt(II)-promoted cleavage of the His8-Thr9 bond in MP-11. These results support the hypothesis that the Pd(II)-mediated cleavage of the His18-Thr19 bond in cytochorome c is due to the identical binding mode.

  DOI：

  10.1021/ic034491a