| 864767-27-1

• CAS: 864767-27-1
• 化学式: C₂₀H₂₇ClO₂Ti
• 分子量: 382.766
• InChiKey: XSHKFAGAWJBRFJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  氯化亚砜 、 以 not given 为溶剂， 以99%的产率得到
  参考文献：
  名称：

  A Modular and Efficient Synthesis of Functional Titanocenes

  摘要：

  A modular synthesis of functional titanocenes featuring building blocks is described. The approach allows straightforward access to large numbers of structurally diverse titanocenes that are pertinent for catalysis, structural studies, and bioinorganic chemistry. Among the functional groups introduced are amino acids, sugars, and fluorescence labels that are attached to the cyclopentadienyl ligand as esters and amides.

  DOI：

  10.1021/ja054185r
• 作为产物：
  描述：

  (五甲基环戊二烯基)三氯化钛(IV) 、 dimethylpyrone 在 叔丁基锂 、 zinc(II) chloride 作用下， 以 not given 为溶剂， 以47%的产率得到
  参考文献：
  名称：

  A Modular and Efficient Synthesis of Functional Titanocenes

  摘要：

  A modular synthesis of functional titanocenes featuring building blocks is described. The approach allows straightforward access to large numbers of structurally diverse titanocenes that are pertinent for catalysis, structural studies, and bioinorganic chemistry. Among the functional groups introduced are amino acids, sugars, and fluorescence labels that are attached to the cyclopentadienyl ligand as esters and amides.

  DOI：

  10.1021/ja054185r

文献信息

• Modular Synthesis of Functional Titanocenes
  作者：Andreas Gansäuer、Iris Winkler、Dennis Worgull、Dieter Franke、Thorsten Lauterbach、Andreas Okkel、Martin Nieger

  DOI：10.1021/om800700c

  日期：2008.11.10

  approach to carbonyl-functionalized titanocenes is described. Through the introduction of highly electrophilic acid chlorides to the complexes, reactions with nucleophiles can be realized that are incompatible with classical methods of titanocene synthesis. The first amino acid functionalized titanocenes were synthesized. The amide- and ketone-functionalized titanocenes are cationic, due to the complexation

  描述了羰基官能化的钛烷的模块化方法。通过向配合物中引入高度亲电的酰基氯，可以实现与亲核试剂的反应，这种反应与经典的钛茂合成方法不兼容。合成了第一个氨基酸功能化的钛烷。由于羰基的络合导致形成未应变的环，因此酰胺和酮官能化的钛烷具有阳离子性。
• CONJUGATES OF 18F CARRIERS HAVING BIOACTIVE, ORGANIC COMPOUNDS AND THE PREPARATION THEREOF
  申请人：Scabini Matteo

  公开号：US20130041104A1

  公开（公告）日：2013-02-14

  The invention relates to novel chemical compounds, which can be fluorinated with 18 F under especially mild conditions. The novel chemical compounds thereby enable the use of a novel fluorination method according to the invention, wherein the substrate to be fluorinated is immobilized on a polymer during the fluorination. The method is characterized in that the method requires fewer and simpler manipulations than methods of the prior art. The occupational safety in the laboratory or hospital is thereby increased especially during work with the radionuclide 18 F.

  本发明涉及一种新的化合物，可以在特别温和的条件下用18F进行氟化。这些新的化合物因此使得根据本发明的新型氟化方法的使用成为可能，其中要氟化的底物在氟化过程中被固定在聚合物上。该方法的特点在于，该方法比现有技术的方法需要更少和更简单的操作。因此，在实验室或医院使用放射性核素18F进行工作时，提高了职业安全性。
• Novel Organometallic Gelators with Enhanced Amphiphilic Character: Structure−Property Correlations, Principles for Design, and Diversity of Gelation
  作者：Andreas Gansäuer、Iris Winkler、Thorsten Klawonn、Roeland J. M. Nolte、Martin C. Feiters、Hans G. Börner、Jens Hentschel、Karl Heinz Dötz

  DOI：10.1021/om801022c

  日期：2009.3.9

  A series of new titanocene complexes was synthesized and investigated toward their gelation abilities. The first structure-property correlations for organometallic gelators could be deduced. The gels and their structural diversity were characterized by TEM, cryo-SEM, and AFM as well as CD-spectroscopy. The organometallic gets display an enhanced amphiphilic character compared to typical organic ALS gelators.