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    首页 分子通 8-(4-chlorobenzyloxy)-5-(4-chlorobenzylsulfonyl)imidazo[1.2-d][1,2,4]triazine

    8-(4-chlorobenzyloxy)-5-(4-chlorobenzylsulfonyl)imidazo[1.2-d][1,2,4]triazine | 212835-77-3

    分子结构分类

    有机化合物 - 有机杂环化合物 - 咪唑并[1，2-d][1，2，4]三嗪
    中文名称
    ——
    中文别名
    ——
    英文名称
    8-(4-chlorobenzyloxy)-5-(4-chlorobenzylsulfonyl)imidazo[1.2-d][1,2,4]triazine
    英文别名
    8-[(4-Chlorophenyl)methoxy]-5-[(4-chlorophenyl)methylsulfonyl]imidazo[1,2-d][1,2,4]triazine
    8-(4-chlorobenzyloxy)-5-(4-chlorobenzylsulfonyl)imidazo[1.2-d][1,2,4]triazine化学式
    CAS
    212835-77-3
    化学式
    C19H14Cl2N4O3S
    mdl
    ——
    分子量
    449.317
    InChiKey
    JSJKDLGLVKGWKP-UHFFFAOYSA-N
    BEILSTEIN
    ——
    EINECS
    ——
    • 物化性质
    • 计算性质
    • ADMET
    • 安全信息
    • SDS
    • 制备方法与用途
    • 上下游信息
    • 反应信息
    • 文献信息
    • 表征谱图
    • 同类化合物
    • 相关功能分类
    • 相关结构分类

    计算性质

    • 辛醇/水分配系数(LogP)：
      4.2
    • 重原子数：
      29
    • 可旋转键数：
      6
    • 环数：
      4.0
    • sp3杂化的碳原子比例：
      0.11
    • 拓扑面积：
      94.8
    • 氢给体数：
      0
    • 氢受体数：
      6

    文献信息

    • TENSION-RELIEVING AGENTS FOR CILIARY MUSCLE
      申请人：Senju Pharmaceutical Co., Ltd.
      公开号：EP1224945A1
      公开（公告）日：2002-07-24
      Use of a chymase inhibitor in preventing and treating nearsightedness caused by the continuous tension of ciliary muscles makes it possible to achieve exact preventive and therapeutic effects with little side effects.
      使用糜蛋白酶抑制剂来预防和治疗因睫状肌持续紧张而引起的近视，可以达到确切的预防和治疗效果，而且副作用很小。
    查看更多

    同类化合物

    咪唑并[1,2-d][1,2,4]三嗪-5(6H)-酮 5-methyl-8-phenylimidazo[1,2-d][1,2,4]triazin-2-ol 7-methyl-7H-imidazo[1,2-d][1,2,4]triazin-8-one 8-benzyl-2,3-dibromoimidazo[1,2-d][1,2,4]triazin-5(6H)-one 2-(2-Ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-5-methyl-8-phenyl-imidazo[1,2-d][1,2,4]triazine 8-(3-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1,2,4]triazin-5-one 3-cyclohexyl-8-(2-fluorophenyl)-5-methyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)imidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-5-methyl-8-phenyl-imidazo[1,2-d][1,2,4]triazine 8-(4-Amino-phenyl)-2,3-dibromo-6H-imidazo[1,2-d][1,2,4]triazin-5-one imidazo[1,2-d][1,2,4]triazin-8(7H)-one 4-N-Morpholino-imidazo<1,5-d>-as-triazin 5-Methylthioimidazo<1,2-d>-as-triazin 6H-imidazo[1,2-d][1,2,4]triazine-5-thione 3-Bromo-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-5-methyl-8-phenyl-imidazo[1,2-d][1,2,4]triazine 2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-5-methyl-8-phenyl-3-(thien-2-yl)-imidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-8-(2,6-difluorophenyl)-5-methyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)imidazo[1,2-d][1,2,4]triazine 4-{5-Methyl-8-oxo-7H,8H-imidazo[1,2-D][1,2,4]triazin-7-YL}-N-(2-phenylethyl)butanamide 3-cyclopentyl-8-(2,6-difluorophenyl)-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-5-methylimidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-5-cyclopropyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-8-phenylimidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-8-(2-fluorophenyl)-5-methyl-2-(3-methyl-3H-[1,2,3]triazol-4-ylmethoxy)imidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-8-(2-fluorophenyl)-5-methyl-2-(1-methyl-1H-[1,2,4]triazol-3-ylmethoxy)imidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-5-ethyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-8-phenylimidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-8-(2-fluorophenyl)-5-methyl-2-(1-methyl-1H-[1,2,3]triazol-4-ylmethoxy)imidazo[1,2-d][1,2,4]triazine 3-cyclobutyl-8-(2-fluorophenyl)-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-imidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-5-methyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-8-phenylimidazo[1,2-d][1,2,4]triazine 3-cyclopentyl-5-ethyl-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-8-phenylimidazo[1,2-d][1,2,4]triazine 8-(4-chlorobenzyloxy)-5-(4-chlorobenzylsulfonyl)imidazo[1.2-d][1,2,4]triazine 3-cyclopentyl-8-(2-fluorophenyl)-5-methyl-2-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)imidazo[1,2-d][1,2,4]triazine N-cyclopentyl-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(1R,2R,3S)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide 2-Tert-butylimidazo[1,2-d][1,2,4]triazine N-[(1R,2R,3R)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(1S,2R,3S)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(1S,2R,3R)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(2S)-butan-2-yl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide 4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)-N-[(2S)-4-phenylbutan-2-yl]butanamide 4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)-N-[(1R)-1-phenylethyl]butanamide 4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)-N-[(1S)-1-phenylethyl]butanamide N-[(1R,2S,3R)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(1R,2S,3S)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(1S,2S,3S)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide N-[(2R)-butan-2-yl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide 4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)-N-[(2R)-4-phenylbutan-2-yl]butanamide N-[(1S,2S,3R)-2,3-dimethylcyclohexyl]-4-(5-methyl-8-oxoimidazo[1,2-d][1,2,4]triazin-7-yl)butanamide 8-Ethyl-3-methylimidazo[1,2-d][1,2,4]triazine Imidazo[1,2-D][1,2,4]triazine

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