3-(Carboxymethyl)-3-methoxy-1,2,4-trioxolane | 143429-23-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三氧戊环
• 英文名称: 3-(Carboxymethyl)-3-methoxy-1,2,4-trioxolane
• 英文别名: Methyl 3-methoxy-1,2,4-trioxolane-3-carboxylate
• CAS: 143429-23-6
• 化学式: C₅H₈O₆
• 分子量: 164.115
• InChiKey: PQTZCMQWYYJRCS-UHFFFAOYSA-N

物化性质

• 沸点：
  169.9±40.0 °C(Predicted)
• 密度：
  1.34±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2-甲氧基-2-丙酸甲酯 在 臭氧 作用下， 反应 3.0h， 以36%的产率得到3-(Carboxymethyl)-3-methoxy-1,2,4-trioxolane
  参考文献：
  名称：

  Ozonolyses of selected vinyl ethers

  摘要：

  Ozonolyses of the 1-substituted methyl vinyl ethers 5, 8, and 16, bearing bulky substituents, and of the 2-substituted and 2,2-disubstituted methyl vinyl ethers 25 and 30, respectively, afforded the corresponding ozonides which have been isolated and characterized. In most cases, dry ozonolysis on polyethylene was advantageous over ozonolysis in solution. Ozonolysis of the 1,2,2-trisubstituted vinyl ether 34 gave no ozonide under either conditions.

  DOI：

  10.1021/jo00047a007

文献信息

• Ozonolyses of selected vinyl ethers
  作者：Karl Griesbaum、Woo Sun Kim

  DOI：10.1021/jo00047a007

  日期：1992.10

  Ozonolyses of the 1-substituted methyl vinyl ethers 5, 8, and 16, bearing bulky substituents, and of the 2-substituted and 2,2-disubstituted methyl vinyl ethers 25 and 30, respectively, afforded the corresponding ozonides which have been isolated and characterized. In most cases, dry ozonolysis on polyethylene was advantageous over ozonolysis in solution. Ozonolysis of the 1,2,2-trisubstituted vinyl ether 34 gave no ozonide under either conditions.