7,10-diboraneyl-7,10-di-tert-butyl-2,3,5,6,7,8,9,10,11,12,14,15-dodecahydro-7l5,10l5-naphtho[2,3-e][1,4,7,10]tetraoxa[13,16]diphosphacyclooctadecine | 1423013-28-8

• 英文名称: 7,10-diboraneyl-7,10-di-tert-butyl-2,3,5,6,7,8,9,10,11,12,14,15-dodecahydro-7l5,10l5-naphtho[2,3-e][1,4,7,10]tetraoxa[13,16]diphosphacyclooctadecine
• CAS: 1423013-28-8
• 化学式: C₂₈H₅₀B₂O₄P₂
• 分子量: 534.272
• InChiKey: OAIPUKQUALITMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  2,3-二羟基萘 在 正丁基锂 、 potassium carbonate 、 sodium hydroxide 作用下， 以 四氢呋喃 、 正己烷 、 水 、 乙腈 为溶剂， 反应 49.0h， 生成 7,10-diboraneyl-7,10-di-tert-butyl-2,3,5,6,7,8,9,10,11,12,14,15-dodecahydro-7l5,10l5-naphtho[2,3-e][1,4,7,10]tetraoxa[13,16]diphosphacyclooctadecine
  参考文献：
  名称：

  Synthesis of Enantiopure P-Stereogenic Diphosphacrowns using P-Stereogenic Secondary Phosphines

  摘要：

  A new synthetic route to enantiopure P-stereogenic benzodiphosphacrowns using a P-stereogenic secondary bisphosphine as the key building block is reported. Syntheses of the enantiomer and P-stereogenic crowns with various ring structures, as well as deboranation of the crown compounds and subsequent reaction with a platinum complex, are described.

  DOI：

  10.1021/jo302748x

文献信息

• P-Stereogenic Diphosphacrowns: Facile Incorporation of Aromatic Rings
  作者：Yasuhiro Morisaki、Yoshiki Chujo、Ryosuke Kato、Hiroyuki Watanabe

  DOI：10.3987/com-15-13324

  日期：——

  P-Stereogenic diphosphacrowns containing naphthalene and pyridine rings were synthesized. Facile incorporation of aromatic rings, and chains of different lengths, into the diphosphacrown skeleton was achieved by altering the electrophile in our previously reported synthetic method. Pyridine-containing diphosphacrown exhibited chiral recognition ability for chiral ammonium salts and carboxylic acids. This is the first example of chiral recognition using P-stereogenic diphosphacrowns. H-1 and P-31 NMR spectra indicated that the nitrogen, oxygen, and chiral phosphorus atoms contributed to the chiral recognition cooperatively.