(8-methylquinolin-1-ium-1-yl)(tosyl)amide | 1274906-15-8

• 英文名称: (8-methylquinolin-1-ium-1-yl)(tosyl)amide
• CAS: 1274906-15-8
• 化学式: C₁₇H₁₆N₂O₂S
• 分子量: 312.392
• InChiKey: QALBSABBARFRGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  3-[6-(tert-butyldimethylsilanyloxy)hex-1-ynyl]oxazolidin-2-one 、 (8-methylquinolin-1-ium-1-yl)(tosyl)amide 在 [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]gold bis(trifluoromethanesulfonyl)imidate 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 48.0h， 生成 N-(6-(tert-butyldimethylsilyloxy)-1-(2-oxooxazolidin-3-yl)hex-2-enylidene)-4-methylbenzenesulfonamide 、 N-(6-(tert-butyldimethylsilyloxy)-1-(2-oxooxazolidin-3-yl)hex-2-enylidene)-4-methylbenzenesulfonamide
  参考文献：
  名称：

  Gold-Catalyzed Nitrene Transfer to Activated Alkynes: Formation of α,β-Unsaturated Amidines

  摘要：

  A gold-catalyzed intermolecular nitrene transfer to alkynes was developed for the first time, revealing a new mode of nitrene transfer and providing a novel access to versatile alpha-imino metal carbenes. Various mild nitrene-transfer reagents were examined, and iminopyridium ylides especially those based on 3,5-dichloropyridine proved be highly effective. With activated alkynes such as N-alkynyloxazolidinones as substrates, alpha,beta-unsaturated amidines were formed in mostly good yields.

  DOI：

  10.1021/ol2002607
• 作为产物：
  描述：

  、 对甲苯磺酰氯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 以20%的产率得到(8-methylquinolin-1-ium-1-yl)(tosyl)amide
  参考文献：
  名称：

  Gold-Catalyzed Nitrene Transfer to Activated Alkynes: Formation of α,β-Unsaturated Amidines

  摘要：

  A gold-catalyzed intermolecular nitrene transfer to alkynes was developed for the first time, revealing a new mode of nitrene transfer and providing a novel access to versatile alpha-imino metal carbenes. Various mild nitrene-transfer reagents were examined, and iminopyridium ylides especially those based on 3,5-dichloropyridine proved be highly effective. With activated alkynes such as N-alkynyloxazolidinones as substrates, alpha,beta-unsaturated amidines were formed in mostly good yields.

  DOI：

  10.1021/ol2002607