[Co(η5-Me4C5H)(C7H9(NO)2C6H9O)] | 1018476-80-6

• 英文名称: [Co(η5-Me4C5H)(C7H9(NO)2C6H9O)]
• CAS: 1018476-80-6
• 化学式: C₂₂H₃₁CoN₂O₃
• 分子量: 430.493
• InChiKey: FQUYINMQXSSBKS-JSSVOPEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  降冰片烯 、 [Co(η5-Me4C5H)(C7H9(NO)2C6H9O)] 以 not given 为溶剂， 生成
  参考文献：
  名称：

  Cobalt Dinitrosoalkane Complexes in the C−H Functionalization of Olefins

  摘要：

  The use of cobalt dinitrosoalkane complexes in the C-H functionalization of alkenes has been demonstrated. Reaction of a series of alkenes with Me(4)CpCo(CO)(2) in the presence of NO generates intermediate cobalt dinitrosoalkane complexes that can be deprotonated M to the nitrosyl group and added to various Michael acceptors. The resultant products can then undergo retrocycloaddition reactions in the presence of the original alkene to regenerate the starting cobalt dinitrosoalkane complex and release the functionalized alkene.

  DOI：

  10.1021/ja800738d
• 作为产物：
  描述：

  2-环己烯-1-酮 、 在 zinc(II) chloride 、 lithium hexamethyldisilazane 作用下， 以 四氢呋喃 、 六甲基磷酰三胺 为溶剂， 以52%的产率得到[Co(η5-Me4C5H)(C7H9(NO)2C6H9O)]
  参考文献：
  名称：

  Cobalt Dinitrosoalkane Complexes in the C−H Functionalization of Olefins

  摘要：

  The use of cobalt dinitrosoalkane complexes in the C-H functionalization of alkenes has been demonstrated. Reaction of a series of alkenes with Me(4)CpCo(CO)(2) in the presence of NO generates intermediate cobalt dinitrosoalkane complexes that can be deprotonated M to the nitrosyl group and added to various Michael acceptors. The resultant products can then undergo retrocycloaddition reactions in the presence of the original alkene to regenerate the starting cobalt dinitrosoalkane complex and release the functionalized alkene.

  DOI：

  10.1021/ja800738d

文献信息

• Cobalt-Mediated, Enantioselective Synthesis of <i>C</i>₂ and <i>C</i>₁ Dienes
  作者：W. Christopher Boyd、Mark R. Crimmin、Lauren E. Rosebrugh、Jennifer M. Schomaker、Robert G. Bergman、F. Dean Toste

  DOI：10.1021/ja107968c

  日期：2010.11.24

  novel base mixture derived from enantiopure ammonium salts and NaHMDS was used as a source of chirality, and this enantioselective desymmetrization of C(s) alkenes has been applied to the asymmetric synthesis of C(2)- and C(1)-symmetric diene ligands in high regioselectivity (3.7-20:1 anti/syn), near perfect diastereoselectivity (>99:1 dr), and high enantioselectivity (90-96% ee).

  由活性中间体 [η(5)-((t)BuMe(2)Si)C(5)H(4) 介导的具有五元、六元和七元环烯酮的降冰片烯和降冰片二烯的不对称 CH 官能化)}Co(NO)(2)] 被报道。一种源自对映纯铵盐和 NaHMDS 的新型碱混合物用作手性来源，C(s) 烯烃的这种对映选择性去对称化已应用于 C(2)-和 C(1)-对称二烯的不对称合成配体具有高区域选择性（3.7-20:1 anti/syn）、近乎完美的非对映选择性（>99:1 dr）和高对映选择性（90-96% ee）。