3,7,10,11,12-Pentaoxatricyclo[7.2.1.02,8]dodeca-1,4,8-triene

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧杂环庚烷类
• 英文名称: 3,7,10,11,12-Pentaoxatricyclo[7.2.1.02,8]dodeca-1,4,8-triene
• 英文别名: 3,7,10,11,12-pentaoxatricyclo[7.2.1.02,8]dodeca-1,4,8-triene
• 化学式: C₇H₄O₅
• 分子量: 168.1
• InChiKey: PSALLPQOVYVCAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• CYCLOPROPYL MODULATORS OF P2Y12 RECEPTOR
  申请人：Auspex Pharmaceuticals, Inc.

  公开号：US20140286943A1

  公开（公告）日：2014-09-25

  The present invention relates to new cyclopropyl modulators of P2Y12 receptor activity, pharmaceutical compositions thereof, and methods of use thereof.

  本发明涉及P2Y12受体活性的新的环丙基调节剂，其制药组合物以及使用方法。
• ENDOSPORE COMPOSITIONS AND USES THEREOF
  申请人：Annuary Healthcare Inc.

  公开号：US20140178496A1

  公开（公告）日：2014-06-26

  Provided herein in some embodiments is a composition that comprises (a) a nanoscale particle(s) or a microscale particle(s); and (b) a film-forming polymer. Also provided herein is a method for an immediate and sustained released formulation suitable for topical administration or administration to surfaces. Further provided herein in certain embodiments is a method of reducing the population of pathogenic microorganisms on skin or surfaces, wherein a method comprises applying to the skin or surface a composition, wherein the composition comprises (a) a nanoscale particle(s) or a microscale particle(s); and (b) a film-forming polymer.