(2E)-3-butyl-2-[(E)-3-(3-butyl-1,3-benzoxazol-3-ium-2-yl)prop-2-enylidene]-1,3-benzoxazole;iodide | 53213-80-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑啉
• 英文名称: (2E)-3-butyl-2-[(E)-3-(3-butyl-1,3-benzoxazol-3-ium-2-yl)prop-2-enylidene]-1,3-benzoxazole;iodide
• CAS: 53213-80-2
• 化学式: C25H29IN2O2
• 分子量: 516.4
• InChiKey: IKVCLKLQOOSIAB-UHFFFAOYSA-M

物化性质

• 溶解度：
  可溶于DMSO

计算性质

• 辛醇/水分配系数(LogP)：
  3.08
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• URINE SAMPLE ANALYSIS DEVICE AND URINE SAMPLE ANALYSIS METHOD
  申请人：Sysmex Corporation

  公开号：EP2963418A1

  公开（公告）日：2016-01-06

  A specimen analysis device 100 prepares a first measurement sample from a urine specimen, a diluting solution 19u having no hemolytic action, and a staining solution 18u that stains membranes, supplies the first measurement sample to a flow cell 51 and emits laser light thereon, thereby receiving fluorescence emitted from the first measurement sample, and obtains a fluorescence signal. Furthermore, the specimen analysis device 100 prepares a second measurement sample from the urine specimen, a diluting solution 19b having a hemolytic action, and a staining solution 18b that stains nuclei, supplies the second measurement sample to the flow cell 51 and emits laser light thereon, thereby receiving fluorescence emitted from the second measurement sample, and obtains a fluorescence signal. Particles not having nucleic acids, including red blood cells, are detected based on information on the fluorescence signal obtained from the first measurement sample, and cells having nucleic acids, including white blood cells, are detected based on information on the fluorescence signal obtained from the second measurement sample.

  标本分析装置 100 从尿液标本中制备第一测量样本、无溶血作用的稀释溶液 19u 和可对膜染色的染色溶液 18u，将第一测量样本提供给流动池 51 并对其发射激光，从而接收第一测量样本发射的荧光，并获得荧光信号。此外，标本分析装置 100 从尿液标本中制备第二测量样本、具有溶血作用的稀释溶液 19b 和可对细胞核染色的染色溶液 18b，将第二测量样本提供给流动池 51 并对其发射激光，从而接收从第二测量样本发射的荧光，并获得荧光信号。根据从第一测量样本获得的荧光信号信息检测不含核酸的颗粒，包括红细胞，根据从第二测量样本获得的荧光信号信息检测含核酸的细胞，包括白细胞。
• URINE ANALYZER AND URINANALYSIS METHOD
  申请人：SYSMEX CORPORATION

  公开号：EP3410114A1

  公开（公告）日：2018-12-05

  The urine analyzer 10 includes a sample preparation unit 30 for mixing a urine sample with a hemolytic agent to prepare a measurement sample, a flow cell 41 for flowing a measurement sample, a light source 42 for irradiating light on the measurement sample flowing through the flow cell 41, a light receiving unit 50 for receiving scattered light given off from the measurement sample by irradiation of light and outputting a scattered light signal, and an analysis unit 12 for detecting fat particles in the measurement sample by using a parameter reflecting the intensity of the scattered light signal output by the light receiving unit 50, and a parameter reflecting the width of the scattered light signal.

  尿液分析仪 10 包括：用于将尿液样本与溶血剂混合以制备测量样本的样本制备单元 30；用于流动测量样本的流动池 41；用于对流经流动池 41 的测量样本进行光照射的光源 42、光接收单元 50，用于接收通过光照射从测量样品发出的散射光并输出散射光信号，以及分析单元 12，用于通过使用反映光接收单元 50 输出的散射光信号强度的参数和反映散射光信号宽度的参数来检测测量样品中的脂肪颗粒。
• RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY
  申请人：Riken

  公开号：EP3686632A1

  公开（公告）日：2020-07-29

  There is provided a radiation dosimetry sol or gel, and a radiation dosimeter containing the sol or the gel as a material for radiation dosimetry. A radiation dosimetry sol or gel characterized by comprising a compound (A) having an excitation light-induced fluorescence property that is changed by a radiolysis product of water; and a silicate salt (B). A radiation dosimetry sol or gel characterized by comprising a compound (A) having an excitation light-induced fluorescence property that is changed by a radiolysis product of water; a silicate salt (B); a water-soluble organic polymer (C) having an organic acid salt structure or an organic acid anion structure; and a dispersant (D) for the silicate salt (B). A radiation dosimeter comprising, as a material for radiation dosimetry, the above-mentioned radiation dosimetry sol or gel.

  提供了一种辐射剂量测定溶胶或凝胶，以及一种含有该溶胶或凝胶作为辐射剂量测定材料的辐射剂量计。 一种辐射剂量测定溶胶或凝胶，其特征在于包含一种化合物 (A)，该化合物具有由水的辐射分解产物改变的激发光诱导荧光特性；以及一种硅酸盐 (B)。 一种辐射剂量计溶胶或凝胶，其特征在于包含一种化合物（A），该化合物具有受水的辐射分解产物影响而改变的激发光诱导荧光特性；一种硅酸盐（B）；一种具有有机酸盐结构或有机酸阴离子结构的水溶性有机聚合物（C）；以及一种用于硅酸盐（B）的分散剂（D）。 一种辐射剂量计，包括作为辐射剂量测定材料的上述辐射剂量测定溶胶或凝胶。
• Sample analyzer and sample analyzing method
  申请人：Sysmex Corporation

  公开号：US10261072B2

  公开（公告）日：2019-04-16

  Disclosed is a sample analyzer for analyzing a sample, including: a preparing unit that mixes a sample, a surfactant-containing diluent, and a nucleic acid staining reagent to prepare a measurement specimen in which nucleic acids of nucleated cells are stained and red blood cells are hemolyzed; a detecting unit that irradiates particles included in the measurement specimen with light to receive scattered light and fluorescence light emitted from the particles and output a detection signal; and a processing unit that counts white blood cells and fungi in the sample based on the detection signal.

  公开了一种用于分析样本的样本分析仪，包括一个制备单元，将样品、含表面活性剂的稀释剂和核酸染色试剂混合，制备测量样本，其中有核细胞的核酸被染色，红细胞被溶血；一个检测单元，用光照射测量样本中的颗粒，接收颗粒发出的散射光和荧光，输出检测信号；以及一个处理单元，根据检测信号计算样本中的白细胞和真菌。
• Urine analyzer and urinalysis method
  申请人：SYSMEX CORPORATION

  公开号：US10775362B2

  公开（公告）日：2020-09-15

  The urine analyzer 10 includes a sample preparation unit 30 for mixing a urine sample with a hemolytic agent to prepare a measurement sample, a flow cell 41 for flowing a measurement sample, a light source 42 for irradiating light on the measurement sample flowing through the flow cell 41, a light receiving unit 50 for receiving scattered light given off from the measurement sample by irradiation of light and outputting a scattered light signal, and an analysis unit 12 for detecting fat particles in the measurement sample by using a parameter reflecting the intensity of the scattered light signal output by the light receiving unit 50, and a parameter reflecting the width of the scattered light signal.

  尿液分析仪 10 包括：用于将尿液样本与溶血剂混合以制备测量样本的样本制备单元 30；用于流动测量样本的流动池 41；用于对流经流动池 41 的测量样本进行光照射的光源 42、光接收单元 50，用于接收通过光照射从测量样品发出的散射光并输出散射光信号，以及分析单元 12，用于通过使用反映光接收单元 50 输出的散射光信号强度的参数和反映散射光信号宽度的参数来检测测量样品中的脂肪颗粒。