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    —— 6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[4-(trifluoromethoxy)phenyl]pyridine-3-carbonitrile —— C25H27F3N4O3
    6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[4-(trifluoromethoxy)phenyl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(4-ethylsulfonylpiperazin-1-yl)-2-[(3R)-3-methyl-4-(3,3,3-trifluoropropanoyl)piperazin-1-yl]pyridine-3-carbonitrile —— C23H31F3N6O3S
    6-cyclopropyl-5-(4-ethylsulfonylpiperazin-1-yl)-2-[(3R)-3-methyl-4-(3,3,3-trifluoropropanoyl)piperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[4-(3-hydroxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-4-methyl-5-(1-prop-2-enoyl-3,6-dihydro-2H-pyridin-5-yl)pyridine-3-carbonitrile —— C28H37N5O3
    6-cyclopropyl-2-[4-(3-hydroxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-4-methyl-5-(1-prop-2-enoyl-3,6-dihydro-2H-pyridin-5-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(4-ethylsulfonylpiperazin-1-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C24H36N6O4S
    6-cyclopropyl-5-(4-ethylsulfonylpiperazin-1-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-5-yl)pyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-5-yl)pyridine-3-carbonitrile
    —— 6-Prop-1-en-2-yl-5-pyridin-4-ylpyridine-3-carbonitrile —— C14H11N3
    6-Prop-1-en-2-yl-5-pyridin-4-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]-4-methylpyridine-3-carbonitrile —— C27H32N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(4-hydroxybutanoyl)piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]pyridine-3-carbonitrile —— C27H32N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(4-hydroxybutanoyl)piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[3-cyclopropyl-4-[(1S,2R)-2-(methoxymethyl)cyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[3-cyclopropyl-4-[(1S,2R)-2-(methoxymethyl)cyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(4-fluorophenyl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carboxylic acid —— C25H30FN3O4
    6-cyclopropyl-5-(4-fluorophenyl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carboxylic acid
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-4-yl)pyridine-3-carbonitrile —— C30H31N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-4-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(1S,2R)-2-(methoxymethyl)cyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(1S,2R)-2-(methoxymethyl)cyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-isoquinolin-4-yl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C27H29N5O2
    6-Cyclopropyl-5-isoquinolin-4-yl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(3R)-3-hydroxybutanoyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile —— C27H31N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(3R)-3-hydroxybutanoyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(4-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carboxylic acid —— C25H30FN3O4
    6-Cyclopropyl-5-(4-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carboxylic acid
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(1H-pyrazol-5-yl)phenyl]pyridine-3-carbonitrile —— C27H30N6O2
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(1H-pyrazol-5-yl)phenyl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-hydroxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-4-methyl-5-(1-prop-2-enoyl-3,6-dihydro-2H-pyridin-5-yl)pyridine-3-carbonitrile —— C28H37N5O3
    6-cyclopropyl-2-[(3R)-4-(3-hydroxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-4-methyl-5-(1-prop-2-enoyl-3,6-dihydro-2H-pyridin-5-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethenylquinazolin-5-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-propan-2-ylpiperazin-1-yl]pyridine-3-carbonitrile —— C29H32N6O2
    6-cyclopropyl-5-(2-ethenylquinazolin-5-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-propan-2-ylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinazolin-5-yl)pyridine-3-carbonitrile —— C29H30N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinazolin-5-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-phenylmethoxypyridine-3-carbonitrile —— C25H30N4O3
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-phenylmethoxypyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(3-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C25H29FN4O2
    6-Cyclopropyl-5-(3-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(2-ethenylpyridin-4-yl)amino]pyridine-3-carbonitrile —— C26H30N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(2-ethenylpyridin-4-yl)amino]pyridine-3-carbonitrile
    —— 6-Cyclopropyl-2-[3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(2-ethenyl-1,7-naphthyridin-4-yl)-4-methylpyridine-3-carbonitrile —— C31H34N6O2
    6-Cyclopropyl-2-[3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(2-ethenyl-1,7-naphthyridin-4-yl)-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-7-yl)pyridine-3-carbonitrile —— C30H31N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-7-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(4-morpholin-4-ylphenyl)pyridine-3-carbonitrile —— C28H35N5O3
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(4-morpholin-4-ylphenyl)pyridine-3-carbonitrile
    —— 6-isopropyl-2-(3-methyl-4-(2-phenylacetyl)piperazin-1-yl)-5-phenylnicotinonitrile 1416138-35-6 C28H30N4O
    6-isopropyl-2-(3-methyl-4-(2-phenylacetyl)piperazin-1-yl)-5-phenylnicotinonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(2-methoxyacetyl)piperazin-1-yl]-5-[(2-ethenylpyridin-4-yl)amino]pyridine-3-carbonitrile —— C26H30N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(2-methoxyacetyl)piperazin-1-yl]-5-[(2-ethenylpyridin-4-yl)amino]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-[(1R,2R)-2-(hydroxymethyl)cyclopropanecarbonyl]-3-methylpiperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C28H29N5O2
    6-cyclopropyl-2-[(3R)-4-[(1R,2R)-2-(hydroxymethyl)cyclopropanecarbonyl]-3-methylpiperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[3-cyclopropyl-4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[3-cyclopropyl-4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-[(4-ethenylpyrimidin-2-yl)amino]-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C24H29N7O2
    6-cyclopropyl-5-[(4-ethenylpyrimidin-2-yl)amino]-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethenylquinazolin-4-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C27H28N6O2
    6-cyclopropyl-5-(2-ethenylquinazolin-4-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]-3-methylpiperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C29H31N5O2
    6-cyclopropyl-2-[(3R)-4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]-3-methylpiperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— [(6S,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-7-methyl-5,5-dioxo-6-prop-2-enyl-5lambda6-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid —— C17H19BrFN3O4S
    [(6S,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-7-methyl-5,5-dioxo-6-prop-2-enyl-5lambda6-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid
    —— 6-cyclopropyl-2-[(3R)-4-(4,4-dimethoxybutanoyl)-3-methylpiperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile —— C27H33N5O3
    6-cyclopropyl-2-[(3R)-4-(4,4-dimethoxybutanoyl)-3-methylpiperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(6-ethenylpyridazin-4-yl)-4-methyl-2-[4-[2-(oxetan-2-yl)acetyl]-3-propan-2-ylpiperazin-1-yl]pyridine-3-carbonitrile —— C28H34N6O2
    6-Cyclopropyl-5-(6-ethenylpyridazin-4-yl)-4-methyl-2-[4-[2-(oxetan-2-yl)acetyl]-3-propan-2-ylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-quinolin-6-ylpyridine-3-carbonitrile —— C27H29N5O2
    6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-quinolin-6-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)pyridine-3-carbonitrile —— C25H28N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]-3-methylpiperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C29H31N5O2
    6-cyclopropyl-2-[4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]-3-methylpiperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C24H31N5O3
    6-cyclopropyl-5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(4-morpholin-4-ylphenyl)pyridine-3-carbonitrile —— C28H35N5O3
    6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(4-morpholin-4-ylphenyl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methyl-5-[3-(pyrrolidine-1-carbonyl)phenyl]pyridine-3-carbonitrile —— C30H37N5O3
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methyl-5-[3-(pyrrolidine-1-carbonyl)phenyl]pyridine-3-carbonitrile
    —— [(6R,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-5,5-dihydroxy-6-(2-hydroxyethyl)-7-methyl-5lambda4-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid —— C16H21BrFN3O5S
    [(6R,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-5,5-dihydroxy-6-(2-hydroxyethyl)-7-methyl-5lambda4-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(2-methoxyacetyl)piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)pyridine-3-carbonitrile —— C25H28N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(2-methoxyacetyl)piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)pyridine-3-carbonitrile
    —— [(6S,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-5,5-dihydroxy-6-(2-hydroxyethyl)-7-methyl-5lambda4-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid —— C16H21BrFN3O5S
    [(6S,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-5,5-dihydroxy-6-(2-hydroxyethyl)-7-methyl-5lambda4-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid
    —— [(6R,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-5,5-dihydroxy-7-methyl-6-prop-2-enyl-5lambda4-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid —— C17H21BrFN3O4S
    [(6R,7R)-7-(5-bromo-2-fluoropyridin-3-yl)-5,5-dihydroxy-7-methyl-6-prop-2-enyl-5lambda4-thia-8-azaspiro[3.5]non-8-en-9-yl]carbamic acid
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinoxalin-5-yl)pyridine-3-carbonitrile —— C29H30N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinoxalin-5-yl)pyridine-3-carbonitrile
    —— 6-isopropyl-5-phenyl-2-(4-(2-phenylacetyl)piperazin-1-yl)nicotinonitrile 1416138-34-5 C27H28N4O
    6-isopropyl-5-phenyl-2-(4-(2-phenylacetyl)piperazin-1-yl)nicotinonitrile
    —— 6-Cyclopropyl-5-[(2-ethenylquinolin-7-yl)amino]-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C29H32N6O2
    6-Cyclopropyl-5-[(2-ethenylquinolin-7-yl)amino]-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-quinoxalin-6-ylpyridine-3-carbonitrile —— C26H28N6O2
    6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-quinoxalin-6-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(4-fluorophenyl)-4-methylpyridine-3-carbonitrile —— C27H31FN4O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(4-fluorophenyl)-4-methylpyridine-3-carbonitrile