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    —— 6-cyclopropyl-5-isoquinolin-5-yl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C28H31N5O2
    6-cyclopropyl-5-isoquinolin-5-yl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— (6R)-6-chloro-5-(2-chloropyridin-4-yl)-6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-1H-pyridine-3-carbonitrile —— C23H27Cl2N5O2
    (6R)-6-chloro-5-(2-chloropyridin-4-yl)-6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-1H-pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[2-[(2R)-oxetan-2-yl]acetyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)-4-methylpyridine-3-carbonitrile —— C29H33N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[2-[(2R)-oxetan-2-yl]acetyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-[2-[(E)-2-(2-ethenylquinoxalin-5-yl)ethenyl]quinoxalin-5-yl]-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C38H36N8O2
    6-cyclopropyl-5-[2-[(E)-2-(2-ethenylquinoxalin-5-yl)ethenyl]quinoxalin-5-yl]-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(1H-indazol-4-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C25H28N6O2
    6-cyclopropyl-5-(1H-indazol-4-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(E)-5-hydroxypent-2-enoyl]piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]pyridine-3-carbonitrile —— C28H32N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(E)-5-hydroxypent-2-enoyl]piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]pyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(6-methoxynaphthalen-2-yl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C30H34N4O3
    6-Cyclopropyl-5-(6-methoxynaphthalen-2-yl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-Cyclopropyl-2-[3-cyclopropyl-4-[2-(oxetan-2-yl)acetyl]piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)pyridine-3-carbonitrile —— C27H30N6O2
    6-Cyclopropyl-2-[3-cyclopropyl-4-[2-(oxetan-2-yl)acetyl]piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)pyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(2-ethenylquinoxalin-5-yl)-2-[4-(3-methoxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C31H36N6O2
    6-Cyclopropyl-5-(2-ethenylquinoxalin-5-yl)-2-[4-(3-methoxypropanoyl)-3-propan-2-ylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(2-ethenylpyridin-4-yl)amino]-4-methylpyridine-3-carbonitrile —— C27H32N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(2-ethenylpyridin-4-yl)amino]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)oxy-4-methylpyridine-3-carbonitrile —— C27H31N5O3
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)oxy-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-[2-[(E)-2-(2-ethenylquinoxalin-5-yl)ethenyl]quinoxalin-5-yl]-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C38H36N8O2
    6-cyclopropyl-5-[2-[(E)-2-(2-ethenylquinoxalin-5-yl)ethenyl]quinoxalin-5-yl]-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)-4-methylpyridine-3-carbonitrile —— C26H30N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-(5-ethenylpyridazin-3-yl)-4-methylpyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-[6-(1-fluoroethenyl)pyrimidin-4-yl]-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C24H27FN6O2
    6-Cyclopropyl-5-[6-(1-fluoroethenyl)pyrimidin-4-yl]-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2,3-difluorophenyl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C25H28F2N4O2
    6-cyclopropyl-5-(2,3-difluorophenyl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(6-ethenylpyridazin-4-yl)-4-methylpyridine-3-carbonitrile —— C27H32N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(6-ethenylpyridazin-4-yl)-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-[(6-ethenylpyridin-3-yl)amino]-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C24H28N6O2
    6-cyclopropyl-5-[(6-ethenylpyridin-3-yl)amino]-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[(1R)-1-phenylethoxy]pyridine-3-carbonitrile —— C26H32N4O3
    6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[(1R)-1-phenylethoxy]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethylphenyl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C27H34N4O2
    6-cyclopropyl-5-(2-ethylphenyl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[2-[(2R)-oxetan-2-yl]acetyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile —— C28H31N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[2-[(2R)-oxetan-2-yl]acetyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(1H-indazol-4-yl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C25H28N6O2
    6-cyclopropyl-5-(1H-indazol-4-yl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— (6Z)-7-methoxy-3-methyl-1-phenyl-7-sulfanylidene-6-(1,3,3-trimethylindol-2-ylidene)pyrazolo[4,3-b][1,4]azaphosphinine —— C24H25N4OPS
    (6Z)-7-methoxy-3-methyl-1-phenyl-7-sulfanylidene-6-(1,3,3-trimethylindol-2-ylidene)pyrazolo[4,3-b][1,4]azaphosphinine
    —— 6-Cyclopropyl-5-[(4-ethenylpyridin-2-yl)amino]-2-[4-(3-methoxypropanoyl)-3-propan-2-ylpiperazin-1-yl]pyridine-3-carbonitrile —— C27H34N6O2
    6-Cyclopropyl-5-[(4-ethenylpyridin-2-yl)amino]-2-[4-(3-methoxypropanoyl)-3-propan-2-ylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclohexyl-2-((3S,5R)-4-(furan-3-carbonyl)-3,5-dimethylpiperazin-1-yl)-4-phenylnicotinonitrile 1416139-05-3 C29H32N4O2
    6-cyclohexyl-2-((3S,5R)-4-(furan-3-carbonyl)-3,5-dimethylpiperazin-1-yl)-4-phenylnicotinonitrile
    —— 6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(trifluoromethoxy)phenyl]pyridine-3-carbonitrile —— C25H27F3N4O3
    6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(trifluoromethoxy)phenyl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[3-(oxolan-2-yl)propanoyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile —— C30H35N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[3-(oxolan-2-yl)propanoyl]piperazin-1-yl]-5-(2-ethenylpyridin-4-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methyl-5-[4-(pyrrolidine-1-carbonyl)phenyl]pyridine-3-carbonitrile —— C30H37N5O3
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methyl-5-[4-(pyrrolidine-1-carbonyl)phenyl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-4-yl)pyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-methoxypropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-4-yl)pyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(4-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C25H29FN4O2
    6-Cyclopropyl-5-(4-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(1H-indol-2-yl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C26H29N5O2
    6-cyclopropyl-5-(1H-indol-2-yl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-(4-bromophenyl)-N-ethyl-2-phenyl-1,4-diazatricyclo[5.4.1.04,12]dodeca-2,5,7(12)-triene-5-carbothioamide —— C25H24BrN3S
    6-(4-bromophenyl)-N-ethyl-2-phenyl-1,4-diazatricyclo[5.4.1.04,12]dodeca-2,5,7(12)-triene-5-carbothioamide
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-[(1S,2R)-2-ethoxycyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethenylquinolin-4-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C29H31N5O2
    6-cyclopropyl-5-(2-ethenylquinolin-4-yl)-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(1H-pyrazol-5-yl)phenyl]pyridine-3-carbonitrile —— C27H30N6O2
    6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(1H-pyrazol-5-yl)phenyl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-[4-(cyclopropylmethyl)piperazin-1-yl]-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C26H38N6O2
    6-cyclopropyl-5-[4-(cyclopropylmethyl)piperazin-1-yl]-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(2H-[1,2,5]oxadiazolo[2,3-a]pyridin-4-yl)pyridine-3-carbonitrile —— C24H28N6O3
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(2H-[1,2,5]oxadiazolo[2,3-a]pyridin-4-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(2-oxo-3H-1,3-benzoxazol-5-yl)pyridine-3-carbonitrile —— C25H27N5O4
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(2-oxo-3H-1,3-benzoxazol-5-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]pyridine-3-carbonitrile —— C26H30N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3-hydroxypropanoyl)piperazin-1-yl]-5-[(4-ethenylpyridin-2-yl)amino]pyridine-3-carbonitrile
    —— 6-Cyclopropyl-5-(2-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C24H27FN4O2
    6-Cyclopropyl-5-(2-fluorophenyl)-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethenylpyridin-4-yl)oxy-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C25H29N5O3
    6-cyclopropyl-5-(2-ethenylpyridin-4-yl)oxy-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— (6E)-7-methoxy-3-methyl-1-phenyl-7-sulfanylidene-6-(1,3,3-trimethylindol-2-ylidene)pyrazolo[4,3-b][1,4]azaphosphinine —— C24H25N4OPS
    (6E)-7-methoxy-3-methyl-1-phenyl-7-sulfanylidene-6-(1,3,3-trimethylindol-2-ylidene)pyrazolo[4,3-b][1,4]azaphosphinine
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3,3,3-trifluoropropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-5-yl)pyridine-3-carbonitrile —— C30H28F3N5O
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(3,3,3-trifluoropropanoyl)piperazin-1-yl]-5-(2-ethenylquinolin-5-yl)pyridine-3-carbonitrile
    —— 6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(pyridin-4-ylamino)pyridine-3-carbonitrile —— C23H28N6O2
    6-Cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(pyridin-4-ylamino)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(quinolin-3-ylamino)pyridine-3-carbonitrile —— C27H30N6O2
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-(quinolin-3-ylamino)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(2,2,2-trifluoroacetyl)-1H-indol-5-yl]pyridine-3-carbonitrile —— C28H28F3N5O3
    6-cyclopropyl-2-[4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-5-[3-(2,2,2-trifluoroacetyl)-1H-indol-5-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethenylquinazolin-5-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile —— C27H28N6O2
    6-cyclopropyl-5-(2-ethenylquinazolin-5-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(2-methoxyacetyl)piperazin-1-yl]-5-(6-ethenylpyridazin-4-yl)pyridine-3-carbonitrile —— C25H28N6O2
    6-cyclopropyl-2-[(3R)-3-cyclopropyl-4-(2-methoxyacetyl)piperazin-1-yl]-5-(6-ethenylpyridazin-4-yl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methyl-5-(4-propoxyphenyl)pyridine-3-carbonitrile —— C28H36N4O3
    6-cyclopropyl-2-[(3R)-4-(3-methoxypropanoyl)-3-methylpiperazin-1-yl]-4-methyl-5-(4-propoxyphenyl)pyridine-3-carbonitrile
    —— 6-cyclopropyl-2-[3-cyclopropyl-4-[(1S,2S)-2-ethoxycyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile —— C31H33N5O2
    6-cyclopropyl-2-[3-cyclopropyl-4-[(1S,2S)-2-ethoxycyclopropanecarbonyl]piperazin-1-yl]-5-isoquinolin-5-ylpyridine-3-carbonitrile
    —— 6-cyclopropyl-5-(2-ethenylpyridin-4-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile —— C25H29N5O2
    6-cyclopropyl-5-(2-ethenylpyridin-4-yl)-2-[(3R)-4-(3-hydroxypropanoyl)-3-methylpiperazin-1-yl]-4-methylpyridine-3-carbonitrile