[Fe2(N,N'-diphenyl-N,N'-di(pyridin-2-yl)oxalohydrazide-H)(dimethylformamide)2Cl4] | 1380516-14-2

• 英文名称: [Fe2(N,N'-diphenyl-N,N'-di(pyridin-2-yl)oxalohydrazide-H)(dimethylformamide)2Cl4]
• 英文别名: [Fe2(Gamp)(DMF)2Cl4]
• CAS: 1380516-14-2
• 化学式: C₃₀H₃₂Cl₄Fe₂N₈O₄
• 分子量: 822.141
• InChiKey: OTCQUZUCKXXKSG-UHFFFAOYSA-H

反应信息

• 作为产物：
  描述：

  N,N'-diphenyl-N,N'-di(pyridin-2-yl)oxalohydrazide 、 tetraethylammonium tetrachloridoferrate(III) 、 N,N-二甲基甲酰胺 在 NaOH 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 生成 [Fe2(N,N'-diphenyl-N,N'-di(pyridin-2-yl)oxalohydrazide-H)(dimethylformamide)2Cl4]
  参考文献：
  名称：

  Efficient nuclease activity of dinuclear iron(III) complex with ligand having carboxamido nitrogen donors

  摘要：

  A new dinucleating ligand N,N'-diphenyl-N,N'-di(pyridin-2-yl)oxalohydrazide (GampH(2)) has been synthesized and GampH(2) gave rise to complex [Fe-2(Gamp)(DMF)(2)Cl-4], 1 with FeCl3 salt and 1 was isolated as shiny blue crystalline solid. The molecular structure of complex 1 was characterized by X-ray crystallography. In this dinuclear complex, Fe-Fe separation was found to be 5.49 angstrom and variable temperature magnetic moment was examined. Electrochemical investigation afforded a quasireversible redox couple with E-1/2 value of 0.144 V vs Ag/AgCl. Complex 1 was efficient in DNA cleavage activity and enhancement of DNA cleavage was observed in the presence of 2-mercaptoethanol and hydrogen peroxide. Investigation of mechanism indicated possible involvement of hydroxyl radical in nuclease activity. (C) 2012 Elsevier By. All rights reserved.

  DOI：

  10.1016/j.inoche.2012.02.042