(1-methyl-5-ferrocenyl-1H-pyrazol-3-yl)methanol | 1309044-83-4

• 英文名称: (1-methyl-5-ferrocenyl-1H-pyrazol-3-yl)methanol
• CAS: 1309044-83-4
• 化学式: C₁₅H₁₆FeN₂O
• 分子量: 296.152
• InChiKey: PZWJJLLHIXKHIV-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  (1-methyl-5-ferrocenyl-1H-pyrazol-3-yl)methanol 在 MnO₂ 作用下， 以 二氯甲烷 为溶剂， 以94%的产率得到5-ferrocenyl-1-methyl-1H-pyrazole-3-carbaldehyde
  参考文献：
  名称：

  Synthesis and properties of 5-ferrocenyl-1H-pyrazole-3-carbaldehydes

  摘要：

  New ferrocene derivatives - ethyl esters of 1-aryl-5-ferrocenyl-1H-pyrazole-3-carboxylic acids were synthesized. The corresponding aldehydes were obtained from acid esters in two steps. The reductive amination reaction of 5-ferrocenyl-1-phenyl-1H-pyrazole-3-carbaldehyde was studied. Several of these compounds were investigated by cyclic voltammetry. All of them exhibited a reversible one-electron oxidation-reduction wave owing to the ferrocene-ferricinium redox couple with a positive shift (0.51-0.69 V) compared with that of ferrocene (0.46 V). The X-ray crystal structure of the ethyl ether 1-(3-chloro-2-fluorophenyl)-5-ferrocenyl-1H-pyrazole-3-carboxylic acid is also presented. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.11.018
• 作为产物：
  描述：

  lithium aluminium tetrahydride 、 ethyl 5-ferrocenyl-1-methyl-1H-pyrazole-3-carboxylate hemihydrate 以 四氢呋喃 、 1,4-二氧六环 为溶剂， 以96%的产率得到(1-methyl-5-ferrocenyl-1H-pyrazol-3-yl)methanol
  参考文献：
  名称：

  Synthesis and properties of 5-ferrocenyl-1H-pyrazole-3-carbaldehydes

  摘要：

  New ferrocene derivatives - ethyl esters of 1-aryl-5-ferrocenyl-1H-pyrazole-3-carboxylic acids were synthesized. The corresponding aldehydes were obtained from acid esters in two steps. The reductive amination reaction of 5-ferrocenyl-1-phenyl-1H-pyrazole-3-carbaldehyde was studied. Several of these compounds were investigated by cyclic voltammetry. All of them exhibited a reversible one-electron oxidation-reduction wave owing to the ferrocene-ferricinium redox couple with a positive shift (0.51-0.69 V) compared with that of ferrocene (0.46 V). The X-ray crystal structure of the ethyl ether 1-(3-chloro-2-fluorophenyl)-5-ferrocenyl-1H-pyrazole-3-carboxylic acid is also presented. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.11.018