[(β-naphthyl)CaBr(thf)₄] | 1542255-12-8

• 英文名称: [(β-naphthyl)CaBr(thf)₄]
• 英文别名: [(β-naphthyl)CaBr(tetrahydrofuran)₄]
• CAS: 1542255-12-8
• 化学式: C₂₆H₃₉BrCaO₄
• 分子量: 535.575
• InChiKey: LVUBYNKNFUIOEP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  四氢呋喃 、 2-溴萘 在 碘 、 calcium 作用下， 反应 6.0h， 生成 [(β-naphthyl)CaBr(thf)₄]
  参考文献：
  名称：

  Arylcalcium halides as substrates in Kumada-type cross-coupling reactions

  摘要：

  A precondition of a Kumada-type cross-coupling reaction with arylcalcium halides is the easy availability of these organometallics. Arylcalcium halides are accessible with high yields via reduction of arylhalides with activated calcium in ethers such as tetrahydrofuran. In order to demonstrate the generality of this Grignard-type reduction of haloarenes, [(4-BrC6H4) CaI(thf)(4)] (1) and [(beta-naphthyl)CaBr(thf)(4)] (2) are prepared. First investigations regarding arylcalcium halides as substrates in cross-coupling reactions are undertaken choosing [(C6H5)CaI(thf)(4)] (3) and [(4-CH3C6H4) CaI(thf)(4)] (4) as the organometallic substrate in a cross-coupling with chlorobenzene and 4-chlorotoluene. The nickel-mediated conversion of arylcalcium iodides and chloroarenes to (substituted) biphenyls proceeds with moderate yields and significant amounts of homo-coupling products are observed. (c) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2013.07.022