Di-1-adamantyltricarbonat | 65815-73-8

• 英文名称: Di-1-adamantyltricarbonat
• 英文别名: Bis(1-adamantyloxycarbonyl) carbonate
• CAS: 65815-73-8
• 化学式: C₂₃H₃₀O₇
• 分子量: 418.487
• InChiKey: YAGLBWMMSZFOFP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  88.1
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  Di-1-adamantyltricarbonat 在 三乙烯二胺 作用下， 以 四氯化碳 为溶剂， 生成 di-1-adamantyl dicarbonate
  参考文献：
  名称：

  Synthetic and kinetic studies on tricarbonates and dicarbonates

  摘要：

  DOI：

  10.1021/jo00406a023
• 作为产物：
  描述：

  光气 、 二氧化碳 、 1-金刚烷醇 生成 Di-1-adamantyltricarbonat
  参考文献：
  名称：

  Synthetic and kinetic studies on tricarbonates and dicarbonates

  摘要：

  DOI：

  10.1021/jo00406a023

文献信息

• Synthesis and Application of N,N-Bis-(1-adamantyloxycarbonyl) Amino Acids.
  作者：Barthélémy Nyasse、Ulf Ragnarsson、Jukka Jokisaari、Risto S. Laitinen、Jon Brunvoll、Jens Spanget-Larsen、Radka K. MIlanova、Hiroyuki Nakata、Ahmad Nasiri、Yoshito Okada

  DOI：10.3891/acta.chem.scand.47-0374

  日期：——

  The preparation of novel bis-(1-adamantyloxycarbonyl) amino acid derivatives has been undertaken and their properties studied. Among them, the p-nitrophenyl esters were subsequently applied to the stepwise synthesis of Leu-enkephalin. In the last coupling step, some hydantoin formation was encountered but it could be nearly completely overcome by working with more concentrated solution. The preparation of a tyrosine derivative presented special problems owing to the existence of the phenolic group in the precursor. The relative stability of 1-adamantyloxycarbonyl as N- and O-protecting groups was also studied.
• KONNECKE, ANDREAS;GREHN, LEIF;RAGNARSSON, ULF, TETRAHEDRON LETT., 31,(1990) N9, C. 2697-2700
  作者：KONNECKE, ANDREAS、GREHN, LEIF、RAGNARSSON, ULF

  DOI：——

  日期：——