2-((1H-1,2,4-triazol-1-yl)methyl)-3-ferrocenyl-1-(2,4-dichlorophenyl)prop-2-en-1-one | 948595-61-7

• 英文名称: 2-((1H-1,2,4-triazol-1-yl)methyl)-3-ferrocenyl-1-(2,4-dichlorophenyl)prop-2-en-1-one
• CAS: 948595-61-7
• 化学式: C₂₂H₁₇Cl₂FeN₃O
• 分子量: 466.149
• InChiKey: IHDNAOIRBLLYHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  甲醇 、 2-((1H-1,2,4-triazol-1-yl)methyl)-3-ferrocenyl-1-(2,4-dichlorophenyl)prop-2-en-1-one 、 sodium tetrahydroborate 在 盐酸 、 碳酸氢钠 作用下， 以 甲醇 、 水 为溶剂， 以69.1%的产率得到2-((1H-1,2,4-triazol-1-yl)methyl)-3-ferrocenyl-1-(2,4-dichlorophenyl)prop-2-en-1-ol
  参考文献：
  名称：

  Synthesis and Biological Activity of 1 H -1,2,4-Triazole Alcohol Derivatives

  摘要：

  Eight new 1H-1,2,4-triazole alcohol derivatives containing a ferrocenyl moiety were synthesized. In addition, four unexpected compounds, which are the hydroxyl of the title compounds being methylated by methanol, were obtained. The structures of all these new compounds have been confirmed with 1H NMR spectra, MS, and elemental analyses. The antifungal and plant growth regulatory activities of these compounds are discussed.

  DOI：

  10.1080/15533170802371224
• 作为产物：
  描述：

  二茂铁甲醛 、 1-(2,4-二氯苯基)-3-(1,2,4-三唑-1-基)丙烷-1-酮 在 哌啶 作用下， 以 溶剂黄146 为溶剂， 生成 2-((1H-1,2,4-triazol-1-yl)methyl)-3-ferrocenyl-1-(2,4-dichlorophenyl)prop-2-en-1-one
  参考文献：
  名称：

  Synthesis and Biological Activity of 1 H -1,2,4-Triazole Alcohol Derivatives

  摘要：

  Eight new 1H-1,2,4-triazole alcohol derivatives containing a ferrocenyl moiety were synthesized. In addition, four unexpected compounds, which are the hydroxyl of the title compounds being methylated by methanol, were obtained. The structures of all these new compounds have been confirmed with 1H NMR spectra, MS, and elemental analyses. The antifungal and plant growth regulatory activities of these compounds are discussed.

  DOI：

  10.1080/15533170802371224