[1,1':3',1"-terphenyl]-2'-yl diethyl phosphate | 1437686-55-9

• 英文名称: [1,1':3',1"-terphenyl]-2'-yl diethyl phosphate
• 英文别名: 2-[Diethoxy(oxido)phosphaniumyl]oxy-1,3-diphenylbenzene
• CAS: 1437686-55-9
• 化学式: C₂₂H₂₃O₄P
• 分子量: 382.396
• InChiKey: BZIKDEQDHMEHNC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  50.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二苯基碘三氟甲烷磺酸盐 在 palladium(II) bis(trifluoromethanesulfonate) dihydrate 、 sodium carbonate 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 2.0h， 生成 [1,1':3',1"-terphenyl]-2'-yl diethyl phosphate
  参考文献：
  名称：

  Palladium(II)-catalyzed ortho -arylation via phosphate-group-directed C–H activation

  摘要：

  Aryl dialkyl phosphate, which is readily available from phenol, was a good substrate for the Pd(II) catalyzed aryl aryl coupling reaction through ortho-C H activation. Although a phosphate group is regarded as a poor coordinating group, highly regioselective ortho-arylation could be achieved by employing Pd(OTf)(2)center dot 2H(2)O and Ar2IOTf as a catalyst and an aryl group source, respectively. The phosphate group of the resulting coupled product can be transformed into an aryl anion via reductive cleavage and used for further C-C bond formation. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.067