4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene | 1374226-10-4

• 英文名称: 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene
• CAS: 1374226-10-4
• 化学式: C₁₈H₁₆BF₂IN₂O
• 分子量: 452.05
• InChiKey: RDYVWAPGFQJJAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  5-(4-hydroxyphenyl)dipyrrin 、 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene 在 potassium carbonate 作用下， 以 丁酮 为溶剂， 反应 96.0h， 以58%的产率得到10-(4-(3-(4-((1H-pyrrol-2-yl)(2H-pyrrol-2-ylidene)methyl)phenoxy)propoxy)phenyl)-5,5-difluoro-5H-5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium
  参考文献：
  名称：

  A novel Bodipy-Dipyrrin fluorescent probe: Synthesis and recognition behaviour towards Fe (II) and Zn (II)

  摘要：

  We present the design, synthesis, characterization and spectral studies for a new Zn (II) and Fe (II) selective fluorescent probe, 4,4-Difluoro-8-{3-[(4-phenoxy-dipyrromethene)propoxy]}-4-bora-3a,4a-diazaindacene (DPYBODPY). DPBODPY consists of a terminal fluorophore and a selective ligand and was designed to detect significant changes in absorbance and/or fluorescence on metal ion binding. The fluorophore is based on the Bodipy unit due to its excellent photophysical properties, while the dipyrrin unit has specific recognition abilities for Fe2+ and Zn2+ ions. The combination of these two structures is optimised to achieve significant spectral changes in the presence of Fe2+ and Zn2+ ions. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.02.006
• 作为产物：
  描述：

  4-(3-氯丙氧基)苯甲醛 在 三乙胺 、 三氟乙酸 、 2,3-二氯-5,6-二氰基-1,4-苯醌 、 sodium iodide 作用下， 以 甲醇 、 乙醚 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 22.25h， 生成 4,4-difluoro-8-[4-((3-iodopropoxy)phenyl)]-4-bora-3a,4a-diazaindacene
  参考文献：
  名称：

  A novel Bodipy-Dipyrrin fluorescent probe: Synthesis and recognition behaviour towards Fe (II) and Zn (II)

  摘要：

  We present the design, synthesis, characterization and spectral studies for a new Zn (II) and Fe (II) selective fluorescent probe, 4,4-Difluoro-8-{3-[(4-phenoxy-dipyrromethene)propoxy]}-4-bora-3a,4a-diazaindacene (DPYBODPY). DPBODPY consists of a terminal fluorophore and a selective ligand and was designed to detect significant changes in absorbance and/or fluorescence on metal ion binding. The fluorophore is based on the Bodipy unit due to its excellent photophysical properties, while the dipyrrin unit has specific recognition abilities for Fe2+ and Zn2+ ions. The combination of these two structures is optimised to achieve significant spectral changes in the presence of Fe2+ and Zn2+ ions. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.02.006