2-amino-1-(4-(octyloxy)phenyl)propan-1-one hydrochloride | 1048735-18-7

• 英文名称: 2-amino-1-(4-(octyloxy)phenyl)propan-1-one hydrochloride
• CAS: 1048735-18-7
• 化学式: C₁₇H₂₇NO₂*ClH
• 分子量: 313.868
• InChiKey: PBHQPQWITSNXQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.38
• 重原子数：
  21.0
• 可旋转键数：
  10.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  52.32
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  2-amino-1-(4-(octyloxy)phenyl)propan-1-one hydrochloride 、 环己基异氰酸酯 在 三乙胺 作用下， 以 丙酮 为溶剂， 生成
  参考文献：
  名称：

  5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  摘要：

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.12.064
• 作为产物：
  描述：

  2,2,2-trifluoro-N-(1-(4-(octyloxy)phenyl)-1-oxopropan-2-yl)acetamide 在 盐酸 作用下， 以 乙醇 为溶剂， 生成 2-amino-1-(4-(octyloxy)phenyl)propan-1-one hydrochloride
  参考文献：
  名称：

  5-Aryl-imidazolin-2-ones as a scaffold for potent antioxidant and memory-improving activity

  摘要：

  A series of 5-phenyl-substituted-N-alkyl-imidazolin-2-ones with potent radical-scavenging activity and lipid peroxidation inhibitory activity was synthesized. Many of the compounds showed memory-improving effect in animal models independent of the inhibitory activity on lipid peroxidation. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.12.064