6,7-Dihydro-5H-pyrano[2,3-d]pyrimidin-2-amine | 88696-61-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃嘧啶类
• 英文名称: 6,7-Dihydro-5H-pyrano[2,3-d]pyrimidin-2-amine
• CAS: 88696-61-1
• 化学式: C₇H₉N₃O
• 分子量: 151.17
• InChiKey: HEXMKDMJESAIEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  61
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Herbicidal sulfonamides
  申请人：ICI AUSTRALIA LIMITED

  公开号：EP0385775A1

  公开（公告）日：1990-09-05

  Compounds of the formula and salts thereof, W and W₁ being independently O or S; A being a nitrogen-containing heterocyclic ring system, E being O, S(O)m or NR₄ where m is 0-2; E₁ being CH₂, CH₂CH₂, CH (C₁-C₄ alkyl), C(C₁-C₄ alkyl)₂ or CH (aryl); R₁ and R₂ are independently hydrogen, halogen or one of a variety of organic substituents. The compounds are effective herbicides.

  该公式化合物及其盐，其中W和W₁独立地为O或S；A为含氮杂环环系统，E为O，S(O)m或NR₄，其中m为0-2；E₁为CH₂，CH₂CH₂，CH（C₁-C₄烷基），C（C₁-C₄烷基）₂或CH（芳基）；R₁和R₂独立地为氢，卤素或多种有机取代基。这些化合物是有效的除草剂。
• Herbicidal sulfonamide derivatives
  申请人：ICI AUSTRALIA LIMITED

  公开号：EP0393999A1

  公开（公告）日：1990-10-24

  Compounds of the formula where Q is an optionally substituted quinazoline ring system, W is oxygen or sulphur, R is one of a range of aliphatic or aromatic hydrocarbon substituents and A is a monocyclic or bicyclic ring system wherein that ring by which A is attached to the remainder of the molecule is a five- or six-membered ring with at least two ring nitrogens. The compounds are effective herbicides.

  该化合物的分子式为Q-W-R-A，其中Q是可选择性取代的喹唑啉环系统，W是氧或硫，R是一系列脂肪或芳香烃基取代物之一，A是一个单环或双环环系统，其中连接A和分子其余部分的环为五元或六元环，至少有两个环氮。这些化合物是有效的除草剂。
• Herbicidal sulfonamides, and preparation and use thereof
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0015683A1

  公开（公告）日：1980-09-17

  Sulfonamides of the general formula wherein R is optionally substituted phenyl or optionally substituted pyridyl; R, is R12 is selected from various organic groups; X is H, CH3, CH30, Cl or OCH2CH3; Y is CH2 or O; and W is 0 or S; and their agriculturally suitable salts, exhibit herbicidal activity. The compounds can be formulated into herbicidal compositions in conventional manner. The compounds of formula I may made by reacting a corresponding sulfonyl thiocyanate or isothiocyanate of the formula RS02NCW with an appropriate aminopyrimidine derivative. The compound of formula II may be made by appropriate alkylation of an alkali metal or alkaline earth metal salt of a corresponding sulfonylthiourea.

  通式如下的磺酰胺类化合物 其中 R 是任选取代的苯基或任选取代的吡啶基； R，是 R12 选自各种有机基团 X 是 H、CH3、CH30、Cl 或 OCH2CH3； Y 是 CH2 或 O；以及 W 是 0 或 S；以及它们在农业上适用的盐类，具有除草活性。这些化合物可按常规方法配制成除草组合物。式 I 的化合物可通过式 RS02NCW 的相应磺酰基硫氰酸盐或异硫氰酸盐与适当的氨基嘧啶衍生物反应制得。式 II 的化合物可通过相应磺酰硫脲的碱金属或碱土金属盐的适当烷基化制得。
• Herbicidal ureas and isoureas, preparation and use thereof, and compositions containing them
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0030139A2

  公开（公告）日：1981-06-10

  Compounds of the formula [wherein R1 represents a (Ra0)2RC· or group (in which Ra is CH3 or C2H5, R is H or optionally substituted hydrocarbyl and T is 0 or = N-OR1111 wherein R1111 is H or C1-4 alkyl or alkenyl) or a 1,3-dioxalan-2-yl, 1,3-dioxan-2-yl, 1,3-dithialan-2-yl, 1,3-dithian-2-yl, 1,3-dithialan-2-yl disulfone or 1,3-dithian-2-yl disulfone group, such group being optionally substituted at the 2-position by an optionally substituted hydrocarbyl group; R2 is H, F, Cl, Br, C1-3 alkyl, NO2, SOCH,, OCH3, SCH3, CF3 or N(CH3)2; R3 is H, F, Cl, Br or CH,; and P is (wherein R. is H or CH3; R5 is H, CH3 or OCH3, W is O or S, R11V is an optionally substituted 1,3,5-triazin-2-yl, pyrimid-2-yl, pyrimid-4-yl,1,2,4-triazin-3-yl, pyrid-2-yl, tetrahydropyrano [2,3e] pyrimid-3-yl, tetrahydrofurano [2,3e] pyrimid-3-yl or cyclopenta[e]pyrimid-2-yl group, W1 is optionally substituted alkoxy or alkylthio and RV1 is an optionally substituted pyrimid-2-yl, 1,3,5-triazin-2-yl, tetrahydrofurano[2,3e] pyrimid-3-yl or cyclopenta[e] pyrimid-2-yl group] exhibit herbicidal and plant growth regulant activity. The compounds can be formulated for agricultural use in conventional manner. The compounds can be prepared by many different processes including reaction of an appropriately substituted benzenesulfonylisocyanate containing an o-ketone functional group protected as the dithiane with an appropriate heterocyclic compound.

  式中的化合物 [其中 R1 代表 (Ra0)2RC- 或 基团（其中 Ra 是 CH3 或 C2H5，R 是 H 或任选取代的烃基，T 是 0 或 = N-OR1111，其中 R1111 是 H 或 C1-4 烷基或烯基）或 1，3-二氧戊环-2-基、1，3-二氧戊环-2-基、1、2-基、1,3-二噻烷-2-基、1,3-二噻烷-2-基、1,3-二噻烷-2-基二砜或 1,3-二噻烷-2-基二砜基团，此类基团可任选在 2 位被任选取代的烃基取代；R2 是 H、F、Cl、Br、C1-3 烷基、NO2、SOCH、OCH3、SCH3、CF3 或 N(CH3)2； R3 是 H、F、Cl、Br 或 CH；和 P 是 (其中 R.是 H 或 CH3；R5 是 H、CH3 或 OCH3，W 是 O 或 S，R11V 是任选取代的 1,3,5-三嗪-2-基、嘧啶-2-基、嘧啶-4-基、1,2,4-三嗪-3-基、吡啶-2-基、四氢吡喃并[2,3e]嘧啶-3-基、四氢呋喃并[2,3e]嘧啶-3-基或环戊并[e]嘧啶-2-基、W1 是任选取代的烷氧基或烷硫基，RV1 是任选取代的嘧啶-2-基、1,3,5-三嗪-2-基、四氢呋喃并[2,3e]嘧啶-3-基或环戊并[e]嘧啶-2-基。这些化合物可按常规方法配制成农用制剂。 这些化合物可通过多种不同工艺制备，包括含有邻酮官能团作为二噻烷保护的适当取代的苯磺酰异氰酸酯与适当的杂环化合物反应。
• Herbicidal acetals and ketals
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0177163A2

  公开（公告）日：1986-04-09

  Sulfonylurea derivatives of formula wherein Q is a heteroaromatic group, e.g. thienyl, or is phenyl or benzyl, each of which carries an acetal or ketal substituent; W is O or S; R is H or CH3; and A is a heterocyclic group, e.g. pyrimidyl or triazinyl; and their agriculturally suitable salts exhibit herbicidal activity. Some also show a plant growth regulant effect. The compounds may be formulated for agricultural use in conventional manner. They may be made by a variety of synthetic routes, e.g. by reacting a sulfonamide of formula QSO2NH2 with the phenyl ester of the appropriate N-heterocyclic-carbamic acid, PhO.CO.NR.A.

  式中的磺酰脲衍生物 其中 Q 为杂芳族基团，如噻吩基，或为苯基或苄基，每个基团都带有一个缩醛或缩酮取代基； W 是 O 或 S R 是 H 或 CH3；以及 A 是杂环基团，如嘧啶基或三嗪基；它们在农业上适用的盐类具有除草活性。有些化合物还具有植物生长调节作用。 这些化合物可按常规方法配制成农用制剂。它们可以通过多种合成途径制得，例如，将式 QSO2NH2 的磺酰胺与适当的 N-杂环氨基甲酸 PhO.CO.NR.A 的苯基酯反应。