bis-μ-diethylthio-bis[dichloroplatinum(II)] | 75899-88-6

• 英文名称: bis-μ-diethylthio-bis[dichloroplatinum(II)]
• 英文别名: cis-[PtCl₂(SEt₂)₂]；[PtPh2(μ-SEt2)]2；Pt2Cl4(diethylsulphide)2
• CAS: 75899-88-6；23045-06-9
• 化学式: C₈H₂₀Cl₄Pt₂S₂
• 分子量: 712.351
• InChiKey: DBFGTMCPWLCKCQ-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  bis-μ-diethylthio-bis[dichloroplatinum(II)] 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 生成 trans-Pt(Et2S)(py)Cl2
  参考文献：
  名称：

  二甲基硫醚和二乙基硫醚在铂（II）配合物中的反式作用比较

  摘要：

  摘要在30°C的甲醇中，研究了多种胺将氯化物[Pt（SEt2）Cl3]-中的反式氯化物置换为二乙基硫化物的动力学。已经研究了以3-氯吡啶为离去基团的逆反应。将速率常数与二甲基硫类似物的相应反应的速率常数进行比较。通常，Et2S配合物更具反应性，但反应率取决于配合物和进入基团的性质。

  DOI：

  10.1016/s0020-1693(00)88916-1
• 作为产物：
  描述：

  trans-dichlorobis(diethyl sulfide)platinum(II) 、 苯基锂 以 乙醚 、 二丁醚 为溶剂， 反应 2.3h， 以75%的产率得到bis-μ-diethylthio-bis[dichloroplatinum(II)]
  参考文献：
  名称：

  Organometallic Complexes Anchored to Conductive Carbon for Electrocatalytic Oxidation of Methane at Low Temperature

  摘要：

  Low-temperature direct methane fuel cells (DMEFCs) offer the opportunity to substantially improve the efficiency of energy production from natural gas. This study focuses on the development of well-defined platinum organometallic complexes covalently anchored to ordered mesoporous carbon (OMC) for electrochemical oxidation of methane in a proton exchange membrane fuel cell at 80 degrees C. A maximum normalized power of 403 mu W/mg Pt was obtained, which was 5 times higher than the power obtained from a modern commercial catalyst and 2 orders of magnitude greater than that from a Pt black catalyst. The observed differences in catalytic activities for oxidation of methane are linked to the chemistry of the tethered catalysts, determined by X-ray photoelectron spectroscopy. The chemistry/activity relationships demonstrate a tangible path for the design of electrocatalytic systems for C-H bond activation that afford superior performance in DMEFC for potential commercial applications.

  DOI：

  10.1021/jacs.5b06392

文献信息

• Reactions of methyl fluorosulphate and triethyloxonium tetrafluoroborate with transition-metal complexes
  作者：Colin Eaborn、Nicholas Farrell、James L. Murphy、Alan Pidcock

  DOI：10.1039/dt9760000058

  日期：——

  Reactions of SFO2(OMe) and [Et3O][BF4] with a variety of transition-metal complexes have been examined and classified as ligand abstraction, oxidative additions, oxidation, ligand alkylation, or reactions in which an anion fragment is abstracted from a ligand. Factors influencing the mode of reaction and the mechanisms of some of the reactions are discussed.

  已经检查了SFO 2（OMe）和[Et 3 O] [BF 4 ]与多种过渡金属配合物的反应，并将其分类为配体抽象，氧化加成，氧化，配体烷基化或其中阴离子片段为从配体中提取。讨论了影响反应方式的因素和某些反应的机理。
• Synthese und reaktionsverhalten asymmetrischer metallacyclen des palladiums und platins
  作者：Hans-Peter Abicht、Kurt Issleib

  DOI：10.1016/0022-328x(85)88040-2

  日期：1985.7

  The preparation, properties and the complexation behaviour of o-lithiobenzyldiorganoarsines are described. Halogen-bridged binuclear complexes of the type [μ-ClR2)]2 (M = Pd, Pt; E = N,P) react with o-LiC6H4CH2ER2 (E = N, P, As), to form asymmetric metallacycles with two different donor atoms in the molecule. Some physical and chemical properties of these interesting complexes are discussed.

  描述了邻-硫代苄基二有机砷的制备，性质和络合行为。卤素-桥连的双核的类型的配合物[μ-CL - [R 2）] 2（M =钯，铂; E = N，P）反应与ö -LiC 6 ħ 4 CH 2 ER 2（E = N，P，如），以在分子中形成具有两个不同供体原子的不对称金属环。讨论了这些有趣的配合物的一些物理和化学性质。
• Exploring the Scope of [Pt₂(4-FC₆H₄)₄(μ-SEt₂)₂] as a Precursor for New Organometallic Platinum(II) and Platinum(IV) Antitumor Agents
  作者：Anna Escolà、Margarita Crespo、Josefina Quirante、Roldán Cortés、Anusha Jayaraman、Josefa Badía、Laura Baldomà、Teresa Calvet、Mercè Font-Bardía、Marta Cascante

  DOI：10.1021/om5000908

  日期：2014.4.14

  The new compound [Pt-2(4-FC6H4)(4)(mu-SEt2)(2)] (A) was prepared and fully characterized. The reactions of compound A with ligands ArCH=NCH2CH2NMe2 (Ar = 2-BrC6H4, 1a; 2,6-Cl2C6H3, 1b; 4-ClC6H4, 1c; 2-Cl,6-FC6H3, 1d) were studied under different conditions and produced platinum(II) compounds [Pt(4-FC6H4)2(ArCH=NCH2CH2NMe2)] (2b-2d), containing a bidentate [N,N'] ligand, as well as cyclometalated platinum(IV) or platinum(II) compounds such as [PtBr(4-FC6H4)(2)(C6H4CH=NCH2CH2NMe2)] (4a) or [PtCl(3-FC6H3)(2-XC6H3)CH=NCH2CH2NMe2)] (5b: X = Cl; 5d: X = F), containing a tridentate [C,N,N'] ligand and either a five (4a) or a seven (5b, 5d) membered metallacycle. These compounds exhibit a great antiproliferative activity against non-small lung cancer cells (A549), and the best result was obtained for compound 2c (IC50 = 0.3 +/- 0.1 mu M). While compounds 5 alter the mobility of plasmid DNA in a similar way to cisplatin, compound 4 was less efficient in removing the supercoils from DNA. In spite of the very low IC50 value obtained for compound 2c, this compound does not interact with DNA, and it is neither an intercalator nor a topoisomerase 1 inhibitor.