1-methyl-2-(trimethylsilylmethyl)-o-carborane | 207131-10-0

• 英文名称: 1-methyl-2-(trimethylsilylmethyl)-o-carborane
• CAS: 207131-10-0
• 化学式: C₇H₂₄B₁₀Si
• 分子量: 244.463
• InChiKey: YWWCXSZFPWXLQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  1-methyl-2-(trimethylsilylmethyl)-o-carborane 在 正丁基锂 、 二氧化碳 作用下， 以 乙醚 、 苯 为溶剂， 以52%的产率得到1-CH₂COOH-2-CH₃-1.2-C₂B₁₀H₁₀
  参考文献：
  名称：

  Study of the transmetallation of silicon derivatives ofo-carboranes on treatment with BunLi

  摘要：

  Silyl-substituted o-carboranes 1-R-2-Me3Si(CH2)(n)-1,2-C2B10H10 (R = Me, Ph; n = 0, 1) undergo transmetallation on treatment with (BuLi)-Li-n to form lithium derivatives of o-carboranes, 1-R-2-Li(CH2)(n)-1,2-C2B10H10, where n = 0, 1. A silicon derivative of o-carborane, 1-Ph-2-(Me3SiCHPh)-1,2-C2B10H10, undergoes neither transmetallation nor metallation at the benzyl CH-group on treatment with (BuLi)-Li-n due to significant steric hindrance.

  DOI：

  10.1007/bf02495657
• 作为产物：
  描述：

  1-methyl-ortho-carborane 、 碘甲基三甲基硅烷 在 正丁基锂 作用下， 以 乙醚 、 苯 为溶剂， 以80%的产率得到1-methyl-2-(trimethylsilylmethyl)-o-carborane
  参考文献：
  名称：

  Study of the transmetallation of silicon derivatives ofo-carboranes on treatment with BunLi

  摘要：

  Silyl-substituted o-carboranes 1-R-2-Me3Si(CH2)(n)-1,2-C2B10H10 (R = Me, Ph; n = 0, 1) undergo transmetallation on treatment with (BuLi)-Li-n to form lithium derivatives of o-carboranes, 1-R-2-Li(CH2)(n)-1,2-C2B10H10, where n = 0, 1. A silicon derivative of o-carborane, 1-Ph-2-(Me3SiCHPh)-1,2-C2B10H10, undergoes neither transmetallation nor metallation at the benzyl CH-group on treatment with (BuLi)-Li-n due to significant steric hindrance.

  DOI：

  10.1007/bf02495657