2-ethoxy-4-(4-methoxy-phenyl)-6-ferrocenyl-nicotinonitrile | 884597-70-0

• 英文名称: 2-ethoxy-4-(4-methoxy-phenyl)-6-ferrocenyl-nicotinonitrile
• CAS: 884597-70-0
• 化学式: C₂₅H₂₂FeN₂O₂
• 分子量: 438.309
• InChiKey: IHMDJXCQISQERE-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1-ferrocenyl-3-(4-methoxyphenyl)prop-2-en-1-one 、 sodium ethanolate 、 丙二腈 以 乙醇 为溶剂， 以70%的产率得到2-ethoxy-4-(4-methoxy-phenyl)-6-ferrocenyl-nicotinonitrile
  参考文献：
  名称：

  An efficient synthesis of ferrocenyl substituted 3-cyanopyridine derivatives under ultrasound irradiation

  摘要：

  An efficient synthesis of 2-alkoxy-4-aryl-6-ferrocenyl-3-cyanopyridines via the condensation of ferrocenyl substituted chalcones with malononitrile in a freshly prepared sodium alkoxide solution under ultrasound irradiation was investigated. Especially noteworthy, the reaction of 1-ferrocenyl-3-(pyridin-2-yl)prop-2-ene-1-one with malononitrile afforded 2-alkoxy-4-pyridyl-6-ferrocenylpyridine, with the loss of CN group on the 3-position of pyridine ring was first observed. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.09.046