dihydrocoumarin chromium tricarbonyl | 131856-59-2

• 英文名称: dihydrocoumarin chromium tricarbonyl
• CAS: 131856-59-2
• 化学式: C₁₂H₈CrO₅
• 分子量: 284.189
• InChiKey: KVGKAVUSQLAMMV-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  氢化肉桂酸内酯 、 六羰基铬 以 四氢呋喃 、 二丁醚 为溶剂， 以28.2%的产率得到dihydrocoumarin chromium tricarbonyl
  参考文献：
  名称：

  Resolution of racemic mixtures of chiral arenechromiumtricarbonyl complexes using a Bakerbond Chiralcel HPLC column

  摘要：

  Racemic mixtures of eight new chiral arenechromiumtricarbonyl complexes were prepared and fully characterized by IR, H-1 and C-13 NMR spectroscopy, mass spectrometry and elemental analysis. These compounds, along with 25 previously reported chiral complexes were used to establish the ability of commercially available chiral HPLC columns to effect resolution of the mixtures. It was found that Bakerbond Chiralcel OD(R) columns, consisting of derivatized cellulose on silica gel, successfully resolve racemic mixtures of most arene complexes with good to excellent results. Some tentative patterns in the effect of functional groups and ring substitution on the separation efficiency have been identified and are discussed. Direct resolution of complex 22, ethyl-ortho-methoxybenzoate Cr(CO)(3), was performed on the semipreparative scale. The resolved enantiomers were characterized by optical rotation measurements and gave the following data: band 1, t(R'1) = 77.8 min, [alpha](21)(589) = +/- 30.0 +/- 4.1 degrees; band 2, t(R'2) = 179.8 min, [alpha](21)(589) = -29.5 +/- 1.0 degrees.

  DOI：

  10.1016/0022-328x(94)05069-n