4,4-difluoro-8-(4-methoxyphenyl)-1,3,5,7-tetramethyl-2,6-di[1-(3-(2-[2-(2-methoxyethoxy)ethoxy]ethoxy)-2-(2-[2-(2-methoxyethoxy)ethoxy]ethoxymethyl)propoxy)-3,6,9,12-tetraoxapentadec-14-ynyl]-4-bora-3a,4a-diaza-s-indacene | 1259292-44-8

• 英文名称: 4,4-difluoro-8-(4-methoxyphenyl)-1,3,5,7-tetramethyl-2,6-di[1-(3-(2-[2-(2-methoxyethoxy)ethoxy]ethoxy)-2-(2-[2-(2-methoxyethoxy)ethoxy]ethoxymethyl)propoxy)-3,6,9,12-tetraoxapentadec-14-ynyl]-4-bora-3a,4a-diaza-s-indacene
• CAS: 1259292-44-8
• 化学式: C₇₈H₁₂₉BF₂N₂O₂₇
• 分子量: 1575.69
• InChiKey: PFDWULBDEKAXAQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  5,5-difluoro-10-(4-methoxyphenyl)-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide 、 1-(3-(2-[2-(2-methoxyethoxy)ethoxy]ethoxy)-2-(2-[2-(2-methoxyethoxy)ethoxy]ethoxymethyl)propoxy)-3,6,9,12-tetraoxapentadec-14-yne 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 为溶剂， 以67%的产率得到4,4-difluoro-8-(4-methoxyphenyl)-1,3,5,7-tetramethyl-2,6-di[1-(3-(2-[2-(2-methoxyethoxy)ethoxy]ethoxy)-2-(2-[2-(2-methoxyethoxy)ethoxy]ethoxymethyl)propoxy)-3,6,9,12-tetraoxapentadec-14-ynyl]-4-bora-3a,4a-diaza-s-indacene
  参考文献：
  名称：

  Highly Water-Soluble Neutral BODIPY Dyes with Controllable Fluorescence Quantum Yields

  摘要：

  A series of novel highly water-soluble neutral BODIPY dyes have been obtained by functionalization of BODIPY dyes with branched oligo(ethylene glycol)methyl ether groups at positions 8, 2 and 6 or 4 and 4'. Use of an ortho-substituent group of branched oligo(ethylene glycol)methyl ether on the meso-phenyl ring of BODIPY dyes and replacement of the fluorine atoms of BODIPY dyes at positions 4 and 4' with methyloxy or ethynyl subunits significantly enhance fluorescence quantum yields of BODIPY dyes.

  DOI：

  10.1021/ol102758z