| 1443788-23-5

• CAS: 1443788-23-5
• 化学式: C₁₀H₂₉Cl₄N₅NbP
• 分子量: 485.066
• InChiKey: HNAJRTMFCUDNTE-UHFFFAOYSA-J

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  五氯化铌 、 三(二甲胺基)膦 以 甲苯 为溶剂， 反应 3.0h， 生成
  参考文献：
  名称：

  Hexamethylphosphorus triamide: A chloride-for-dimethylamido, Me2N−, exchange reagent

  摘要：

  The reaction of P(NMe2)(3) with WCl6 produces [ClP(NMe2)(3)][WCl4(NMe2)(2)], [ClP(NMe2)(3)][2], through apparent Cl--for-NMe2- exchange. A six-coordinate [Cl5W-PCl(NMe2)(3)] metallophosphorane species is proposed as a probable intermediate in this ligand exchange reaction. A similar reaction with NbCl5 results in a more complex product, [NbCl4(NHMe2)(eta(2)-N(Me)-C(H)-P(NMe2)(3))], 3, in which Cl--for-NMe2- exchange is attended by additional reactions that include C-H activation and cyclometallation of an NMe2- ligand, H+ transfer to NMe2- to form a dimethylamine ligand, and adduct formation between exogenous P(NMe2)(3) and the formyliminium carbon resulting from cyclometallation. Structural characterization of [ClP(NMe2)(3)][2] reveals a cis disposition of NMe2- ligands that are oriented at 63.2 degrees relative to one another and an appreciable lengthening of the W-Cl bonds trans to the NMe2- ligands (2.4615[4] angstrom) as compared to those that are cis (2.3918[4] angstrom). The structure of 3 is distorted pentagonal bipyramidal with the formyliminium carbon and nitrogen atoms arranged slightly above and below by similar to 0.37 angstrom the equatorial plane. The potential synthetic utility of P(NMe2)(3) as an alternative to the classical method of delivery of dialkylamido ligands via LiNR2 is discussed. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.08.031