σ-(Pt[1H-1-methyl-2-(2'-pyridinyl)-indolyl-C(3),N'](DMSO)Cl) | 310413-96-8

• 英文名称: σ-(Pt[1H-1-methyl-2-(2'-pyridinyl)-indolyl-C(3),N'](DMSO)Cl)
• 英文别名: σ-(Pt[1H-indole-1-methyl-2-(2'-pyridinyl-C(3),N'](DMSO)Cl)
• CAS: 310413-96-8
• 化学式: C₁₆H₁₇ClN₂OPtS
• 分子量: 515.923
• InChiKey: RKOADKFRVQBSFB-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  σ-(Pt[1H-1-methyl-2-(2'-pyridinyl)-indolyl-C(3),N'](DMSO)Cl) 、 一氧化碳 在 triethylamine 作用下， 以 二氯甲烷 为溶剂， 以81%的产率得到σ-(Pt[1H-1-methyl-2-(2'-pyridinyl)-indolyl-C(3),N'](CO)Cl)
  参考文献：
  名称：

  Carbene complexes of cycloplatinated 1H-indole-1-methyl-2-(2′-pyridine). The crystal and molecular structure of σ-{Pt[1H-indole-1-methyl-2-(2′-pyridinyl-C3,N′](DMSO)Cl} and of σ-{Pt[1H-indole-1-methyl-2-(2′-pyridinyl-C3,N′)][C(OCH2CH3)(CH2C6H5)]Cl}

  摘要：

  Reaction of 1-methyl-2-(2'-pyridinyl)-1H-indole (1) with PtCl2(DMSO)(2) (DMSO = dimethylsulfoxide) gave the cycloplatinated product 2; X-ray structure determination of 2 showed a metallation to platinum via the C3 carbon of the indole nucleus, which is chelated to the metal via the pyridine nitrogen atom. Compound 2 reacts with neutral ligands such as CO, Bu'NC, styrene and phenylacetylene, to give compounds 3-6 respectively, where DMSO is replaced by the neutral ligands. The phenylacetylene derivative 6 reacts with ethanol to give the carbene complex 7, whose X-ray structure has been determined. Related carbene complexes with other alcohols and other acetylenic derivatives have also been synthesised. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00343-0
• 作为产物：
  描述：

  dichlorobis(dimethyl sulfoxide)platinum(II) 、 sodium acetate 、 1-methyl-2-(pyridin-2-yl)-1H-indole 以 异丙醇 为溶剂， 以71%的产率得到σ-(Pt[1H-1-methyl-2-(2'-pyridinyl)-indolyl-C(3),N'](DMSO)Cl)
  参考文献：
  名称：

  Carbene complexes of cycloplatinated 1H-indole-1-methyl-2-(2′-pyridine). The crystal and molecular structure of σ-{Pt[1H-indole-1-methyl-2-(2′-pyridinyl-C3,N′](DMSO)Cl} and of σ-{Pt[1H-indole-1-methyl-2-(2′-pyridinyl-C3,N′)][C(OCH2CH3)(CH2C6H5)]Cl}

  摘要：

  Reaction of 1-methyl-2-(2'-pyridinyl)-1H-indole (1) with PtCl2(DMSO)(2) (DMSO = dimethylsulfoxide) gave the cycloplatinated product 2; X-ray structure determination of 2 showed a metallation to platinum via the C3 carbon of the indole nucleus, which is chelated to the metal via the pyridine nitrogen atom. Compound 2 reacts with neutral ligands such as CO, Bu'NC, styrene and phenylacetylene, to give compounds 3-6 respectively, where DMSO is replaced by the neutral ligands. The phenylacetylene derivative 6 reacts with ethanol to give the carbene complex 7, whose X-ray structure has been determined. Related carbene complexes with other alcohols and other acetylenic derivatives have also been synthesised. (C) 2000 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(00)00343-0