Perfluorobicyclo<2.2.0>hexane | 356-11-6

• 英文名称: Perfluorobicyclo<2.2.0>hexane
• 英文别名: decafluoro-bicyclo[2.2.0]hexane；Decafluor-bicyclo[2.2.0]hexan；Decafluorbicyclo<2.2.O>hexan；1,2,2,3,3,4,5,5,6,6-Decafluorobicyclo[2.2.0]hexane
• CAS: 356-11-6
• 化学式: C₆F₁₀
• 分子量: 262.05
• InChiKey: MSISKKFESUNLNM-UHFFFAOYSA-N

物化性质

• 熔点：
  41 °C
• 沸点：
  42.5-43.0 °C
• 密度：
  1.80±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  Perfluorobicyclo<2.2.0>hexane 反应 100.0h， 生成 Perfluoro-1,5-hexadiene 、 Perfluorobicyclo<2.1.1>hexane
  参考文献：
  名称：

  Interrelationships among C6F10 valence isomers

  摘要：

  Thermal and photochemical interconversions among the three valence isomers perfluoro-1,5-hexadiene (1), perfluorobicyclo[2.2.0]hexane(2), and perfluorobicyclo[2.1.1]hexane (3) have been explored. At 250-degrees-C 1 and 2 exist in equilibrium with K1-->2 = 1.1, but at higher temperatures irreversible isomerization to 3 becomes rapid. This chemistry contrasts sharply with the behavior of the corresponding hydrocarbons, where the diene is lowest in free energy. Mercury-sensitized photolysis of diene 1 yields 3 and 2 in ratios of 3-4:1. The cleanness of both the thermal and the photochemistry, together with thermodynamics favorable to cyclization, bode well for synthesizing new bicyclic and polycyclic fluorocarbons from other unsaturated precursors.

  DOI：

  10.1021/jo00075a040
• 作为产物：
  描述：

  1,2,3,4,5,6-六氟-双环(2.2.0)己-2,5-二烯 在 六氟苯 、 fluorine 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 生成 Perfluorobicyclo<2.2.0>hexane
  参考文献：
  名称：

  Interrelationships among C6F10 valence isomers

  摘要：

  Thermal and photochemical interconversions among the three valence isomers perfluoro-1,5-hexadiene (1), perfluorobicyclo[2.2.0]hexane(2), and perfluorobicyclo[2.1.1]hexane (3) have been explored. At 250-degrees-C 1 and 2 exist in equilibrium with K1-->2 = 1.1, but at higher temperatures irreversible isomerization to 3 becomes rapid. This chemistry contrasts sharply with the behavior of the corresponding hydrocarbons, where the diene is lowest in free energy. Mercury-sensitized photolysis of diene 1 yields 3 and 2 in ratios of 3-4:1. The cleanness of both the thermal and the photochemistry, together with thermodynamics favorable to cyclization, bode well for synthesizing new bicyclic and polycyclic fluorocarbons from other unsaturated precursors.

  DOI：

  10.1021/jo00075a040

文献信息

• AUTOMATED CARBOHYDRATE SYNTHESIS
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US20160222048A1

  公开（公告）日：2016-08-04

  The present invention provides a method of preparing an isolated oligosaccharide or glycolipid by preparing the oligosaccharide or glycolipid having a hydrophobic group, such as a perfluorinated alkyl or a fatty acid, and separating the oligosaccharide or glycolipid using a solid-phase extraction cartridge.

  本发明提供了一种通过准备具有疏水基团的寡糖或糖脂，例如全氟烷基或脂肪酸，并使用固相萃取柱分离寡糖或糖脂的方法。
• Preparation of glycosphingosines
  申请人：The Regents of the University of California

  公开号：US10428101B2

  公开（公告）日：2019-10-01

  The present invention provides a method of preparing an isolated oligosaccharide or glycolipid by preparing the oligosaccharide or glycolipid having a hydrophobic group, such as a perfluorinated alkyl or a fatty acid, and separating the oligosaccharide or glycolipid using a solid-phase extraction cartridge.

  本发明提供了一种分离寡糖或糖脂的制备方法，即制备具有疏水基团（如全氟烷基或脂肪酸）的寡糖或糖脂，并使用固相萃取柱分离寡糖或糖脂。
• Preferential Replacement Reactions of Highly Fluorinated Alkyl Halides. II.¹ Some Reactions of Fluorinated Allyl Iodides^2,3
  作者：Arnold H. Fainberg、William T. Miller

  DOI：10.1021/ja01572a050

  日期：1957.8