(2-(boraneylbis(3,5-dimethylphenyl)-l5-phosphaneyl)-1-phenylallyl)diphenylphosphine oxide | 1198309-41-9

• 英文名称: (2-(boraneylbis(3,5-dimethylphenyl)-l5-phosphaneyl)-1-phenylallyl)diphenylphosphine oxide
• CAS: 1198309-41-9
• 化学式: C₃₇H₃₉BOP₂
• 分子量: 572.475
• InChiKey: HRQDVUVLFRTOJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  bis(3,5-dimethylphenyl)phosphine-borane 、 diphenyl(1-phenylpropa-1,2-dien-1-yl)phosphine oxide 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 、 mineral oil 为溶剂， 反应 0.5h， 以83%的产率得到(2-(boraneylbis(3,5-dimethylphenyl)-l5-phosphaneyl)-1-phenylallyl)diphenylphosphine oxide
  参考文献：
  名称：

  Ambient Temperature Hydrophosphination of Internal, Unactivated Alkynes and Allenyl Phosphineoxides with Phosphine Borane Complexes

  摘要：

  Phosphine boranes have been found to hydrophosphinate internal, unactivated alkynes at room temperature under basic conditions without the need for catalysts or radical initiators, The use of air-sensitive secondary phosphines is avoided in this facile process. Broad scope in both the phosphine borane and alkyne partners leads to excellent diversity in the phosphine products. Asymmetric hydrogenation of these species then provides one of the shortest possible routes to chiral monodentate phosphines, Hydrophosphination of allenyl phosphine oxides under similar conditions followed by hydrogenation of the exomethylene moiety yields a wide variety of bis-phosphine derivatives.

  DOI：

  10.1021/ol9022547