| 1609556-36-6

• CAS: 1609556-36-6
• 化学式: C₁₀H₁₆B₁₀
• 分子量: 244.347
• InChiKey: ISSXENRGTRZAMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  在 三(2-甲氧基苯基)膦 、 palladium diacetate 、 caesium carbonate 作用下， 以 四氢呋喃 为溶剂， 反应 12.0h， 以50%的产率得到
  参考文献：
  名称：

  Palladium-Catalyzed Regioselective Intramolecular Coupling of o-Carborane with Aromatics via Direct Cage B–H Activation

  摘要：

  Palladium-catalyzed intramolecular coupling of o-carborane with aromatics via direct cage B-H bond activation has been achieved, leading to the synthesis of a series of o-carborane-functionalized aromatics in high yields with excellent regioselectivity. In addition, the site selectivity can also be tuned by the substituents on cage carbon atom.

  DOI：

  10.1021/jacs.5b01169

文献信息

• Transition-Metal-Mediated Three-Component Cascade Cyclization: Selective Cage B–C(sp²) Coupling of Carborane with Aromatics and Synthesis of Carborane-Fused Tricyclics
  作者：Yangjian Quan、Zaozao Qiu、Zuowei Xie

  DOI：10.1021/ja503489b

  日期：2014.5.28

  Zirconium/nickel comediated one-pot three-component cascade cyclization of carboryne, alkene, and 2-bromophenyltrimethylsilylacetylene has been achieved, leading to the formation of a series of C,C,B-substituted carborane-fused tricyclics. On the basis of experimental results, a plausible mechanism is proposed including [2 + 2 + 1] cross-cyclotrimerization followed by intramolecular direct selective cage B-C(sp(2)) coupling. This represents the first example of direct cage B-C(phenyl) coupling via cage B-H activation.