| 1313028-52-2

• CAS: 1313028-52-2；1313028-54-4
• 化学式: C₄₀H₄₀BFeOP
• 分子量: 634.389
• InChiKey: BIPMSDJTBADHKO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  cyclopenta-1,3-diene;iron(2+);[2-[(S)-(4-methylphenyl)sulfinyl]cyclopenta-1,3-dien-1-yl]-bis(2,4,6-trimethylphenyl)borane 、 二苯基次膦酰氯 在 tert-butyllithium 作用下， 以 四氢呋喃 、 正戊烷 为溶剂， 以60%的产率得到
  参考文献：
  名称：

  Syntheses of homochiral 1,2-ferrocene-functionalized Lewis acids and acid/base pairs

  摘要：

  We report a facile approach for the synthesis of homochiral 1,2-disubstituted ferrocene-functionalized Lewis acids and acid/base pairs. The synthesis is based on chiral induction facilitated by the ortho sulfinyl subsitutent in S-Fc{S(O)p-tol}, S-1, to obtain the key intermediate S,S-p-1,2-fc{S(O)p-tol}(BMes(2)), S,S-p-2a (p-tol = C6H4Me-4, Mes = C6H2Me3-2,4,6). Subsequent substitution of the -S(O)p-tol substituent in S,S-p-2a gives access to a range of enantiomerically pure S-p-1,2-ferrocene-functionalized Lewis acids and acid/base pairs including the first homochiral 1-phosphino-2-borylferrocene. Enantiomeric excesses (e.e.s) of >95% have typically been achieved using this methodology. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2011.03.026